The associations between endothelial lipase 584C/T polymorphism and HDL-C level and coronary heart disease susceptibility: a meta-analysis

Table 1 Main characteristics of studies involved in this meta-analysis of EL 584C/T polymorphism and CHD risk

First author	Year	Ethnicity	Type of study	Mean age (years) (case/control)	Sample size (case/control)	Total sample size	Case (N)			Control (N)			MAF (control)	HWE (P)
			Type of study	Mean age (years) (case/control)	Sample size (case/control)	Total sample size	CC	CT	TT	CC	CT	TT	MAF (control)	HWE (P)
Rimm[30]	1992	Caucasian	nested C-C	66/66	262/519	781	129	117	16	240	239	40	0.31	0.06
Colditz[29]	1997	Caucasian	nested C-C	62/62	241/477	718	115	110	16	224	214	39	0.31	0.22
Shimizu[13]	2007	Asian	C-C	60/58	107/107	214	70	36	1	54	50	3	0.26	0.03
Zhu[17]	2007	Asian	C-C	65/60	242/196	438	186	56	0	150	46	0	0.12	0.06
Tjonneland^a[28]	2007	Caucasian	nested C-C	60/56	235/763	998	116	102	17	391	312	60	0.28	0.84
Tjonneland^b[28]	2007	Caucasian	nested C-C	58/56	763/880	1643	393	304	66	446	361	73	0.29	1.00
Tang[12]	2008	Asian	C-C	63/62	265/265	530	174	85	6	125	122	18	0.30	0.10
Vergeer[16]	2010	Caucasian	nested C-C	-/-	597/1271	1868	97	413	87	207	857	207	0.50	<0.01
Cai[15]	2012	Asian	C-C	63/60	324/299	623	195	116	13	168	122	9	0.23	0.02

^aWomen cohort in the study; ^bMen cohort in the study; C-C: case–control; MAF: minor allelic frequency; HWE: Hardy-Weinberg equilibrium; N: number.

ISSN: 1476-511X