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Table 1 Main characteristics of studies involved in this meta-analysis of EL 584C/T polymorphism and CHD risk

From: The associations between endothelial lipase 584C/T polymorphism and HDL-C level and coronary heart disease susceptibility: a meta-analysis

First author Year Ethnicity Type of study Mean age (years) (case/control) Sample size (case/control) Total sample size Case (N) Control (N) MAF (control) HWE (P)
  CC CT TT CC CT TT
Rimm[30] 1992 Caucasian nested C-C 66/66 262/519 781 129 117 16 240 239 40 0.31 0.06
Colditz[29] 1997 Caucasian nested C-C 62/62 241/477 718 115 110 16 224 214 39 0.31 0.22
Shimizu[13] 2007 Asian C-C 60/58 107/107 214 70 36 1 54 50 3 0.26 0.03
Zhu[17] 2007 Asian C-C 65/60 242/196 438 186 56 0 150 46 0 0.12 0.06
Tjonnelanda[28] 2007 Caucasian nested C-C 60/56 235/763 998 116 102 17 391 312 60 0.28 0.84
Tjonnelandb[28] 2007 Caucasian nested C-C 58/56 763/880 1643 393 304 66 446 361 73 0.29 1.00
Tang[12] 2008 Asian C-C 63/62 265/265 530 174 85 6 125 122 18 0.30 0.10
Vergeer[16] 2010 Caucasian nested C-C -/- 597/1271 1868 97 413 87 207 857 207 0.50 <0.01
Cai[15] 2012 Asian C-C 63/60 324/299 623 195 116 13 168 122 9 0.23 0.02
  1. aWomen cohort in the study; bMen cohort in the study; C-C: case–control; MAF: minor allelic frequency; HWE: Hardy-Weinberg equilibrium; N: number.