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Table 3 Meta-analysis results of association between EL 584C/T polymorphism and CHD risk

From: The associations between endothelial lipase 584C/T polymorphism and HDL-C level and coronary heart disease susceptibility: a meta-analysis

 

Number of studies

Case sample

Control sample

TT vs CC + CT

CT + TT vs CC

T vs C

TT vs CC

OR(95%)

P OR

P Q

I2(%)

OR(95%)

P OR

P Q

I2(%)

OR(95%)

P OR

P Q

I2(%)

OR(95%)

P OR

P Q

I2(%)

Total

9

3036

4777

0.876(0.738-1.041)

0.133

0.389

5.4

0.829(0.701-0.980)

0.028

0.008

61.3

0.882(0.779-0.999)

0.049

0.011

59.5

0.859(0.709-1.040)

0.120

0.185

30.4

Ethnicity

                   

Asian

4

938

867

0.632(0.355-1.125)

0.119

0.070

62.4

0.687(0.486-0.971)

0.034

0.031

66.2

0.727(0.532-0.993)

0.045

0.021

69.3

0.529(0.297-0.945)

0.032

0.035

70.2

Caucasian

5

2098

3910

0.905(0.756-1.084)

0.279

0.889

0.0

0.928(0.813-1.060)

0.272

0.278

21.4

0.969(0.894-1.051)

0.454

0.934

0.0

0.912(0.745-1.117)

0.375

0.905

0.0

Total sample size

                   

<600

3

614

568

0.319(0.134-0.761)

0.010

0.982

0.0

0.631(0.401-0.993)

0.047

0.042

68.4

0.659(0.463-0.937)

0.020

0.079

60.5

0.242(0.100-0.583)

0.002

0.955

0.0

≥600

6

2422

4209

0.920(0.772-1.098)

0.357

0.862

0.0

0.920(0.822-1.031)

0.152

0.371

7.1

0.965(0.893-1.043)

0.368

0.964

0.0

0.927(0.761-1.129)

0.452

0.914

0.0

HWE

                   

Yes

5

2008

3100

0.859(0.681-1.085)

0.202

0.220

30.3

0.827(0.662-1.033)

0.093

0.005

69.9

0.879(0.736-1.049)

0.152

0.006

69.1

0.832(0.654-1.057)

0.132

0.083

51.5

No

4

1028

1677

0.898(0.695-1.160)

0.409

0.443

0.0

0.833(0.623-1.116)

0.221

0.132

50.7

0.891(0.733-1.083)

0.245

0.173

42.9

0.910(0.662-1.251)

0.563

0.434

0.0