| Number of studies | Case sample | Control sample | TT vs CC + CT | CT + TT vs CC | T vs C | TT vs CC | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR(95%) | P OR | P Q | I2(%) | OR(95%) | P OR | P Q | I2(%) | OR(95%) | P OR | P Q | I2(%) | OR(95%) | P OR | P Q | I2(%) | ||||
Total | 9 | 3036 | 4777 | 0.876(0.738-1.041) | 0.133 | 0.389 | 5.4 | 0.829(0.701-0.980) | 0.028 | 0.008 | 61.3 | 0.882(0.779-0.999) | 0.049 | 0.011 | 59.5 | 0.859(0.709-1.040) | 0.120 | 0.185 | 30.4 |
Ethnicity | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Asian | 4 | 938 | 867 | 0.632(0.355-1.125) | 0.119 | 0.070 | 62.4 | 0.687(0.486-0.971) | 0.034 | 0.031 | 66.2 | 0.727(0.532-0.993) | 0.045 | 0.021 | 69.3 | 0.529(0.297-0.945) | 0.032 | 0.035 | 70.2 |
Caucasian | 5 | 2098 | 3910 | 0.905(0.756-1.084) | 0.279 | 0.889 | 0.0 | 0.928(0.813-1.060) | 0.272 | 0.278 | 21.4 | 0.969(0.894-1.051) | 0.454 | 0.934 | 0.0 | 0.912(0.745-1.117) | 0.375 | 0.905 | 0.0 |
Total sample size | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
<600 | 3 | 614 | 568 | 0.319(0.134-0.761) | 0.010 | 0.982 | 0.0 | 0.631(0.401-0.993) | 0.047 | 0.042 | 68.4 | 0.659(0.463-0.937) | 0.020 | 0.079 | 60.5 | 0.242(0.100-0.583) | 0.002 | 0.955 | 0.0 |
≥600 | 6 | 2422 | 4209 | 0.920(0.772-1.098) | 0.357 | 0.862 | 0.0 | 0.920(0.822-1.031) | 0.152 | 0.371 | 7.1 | 0.965(0.893-1.043) | 0.368 | 0.964 | 0.0 | 0.927(0.761-1.129) | 0.452 | 0.914 | 0.0 |
HWE | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Yes | 5 | 2008 | 3100 | 0.859(0.681-1.085) | 0.202 | 0.220 | 30.3 | 0.827(0.662-1.033) | 0.093 | 0.005 | 69.9 | 0.879(0.736-1.049) | 0.152 | 0.006 | 69.1 | 0.832(0.654-1.057) | 0.132 | 0.083 | 51.5 |
No | 4 | 1028 | 1677 | 0.898(0.695-1.160) | 0.409 | 0.443 | 0.0 | 0.833(0.623-1.116) | 0.221 | 0.132 | 50.7 | 0.891(0.733-1.083) | 0.245 | 0.173 | 42.9 | 0.910(0.662-1.251) | 0.563 | 0.434 | 0.0 |