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Table 3 Meta-analysis results of association between EL 584C/T polymorphism and CHD risk

From: The associations between endothelial lipase 584C/T polymorphism and HDL-C level and coronary heart disease susceptibility: a meta-analysis

  Number of studies Case sample Control sample TT vs CC + CT CT + TT vs CC T vs C TT vs CC
OR(95%) P OR P Q I2(%) OR(95%) P OR P Q I2(%) OR(95%) P OR P Q I2(%) OR(95%) P OR P Q I2(%)
Total 9 3036 4777 0.876(0.738-1.041) 0.133 0.389 5.4 0.829(0.701-0.980) 0.028 0.008 61.3 0.882(0.779-0.999) 0.049 0.011 59.5 0.859(0.709-1.040) 0.120 0.185 30.4
Ethnicity                    
Asian 4 938 867 0.632(0.355-1.125) 0.119 0.070 62.4 0.687(0.486-0.971) 0.034 0.031 66.2 0.727(0.532-0.993) 0.045 0.021 69.3 0.529(0.297-0.945) 0.032 0.035 70.2
Caucasian 5 2098 3910 0.905(0.756-1.084) 0.279 0.889 0.0 0.928(0.813-1.060) 0.272 0.278 21.4 0.969(0.894-1.051) 0.454 0.934 0.0 0.912(0.745-1.117) 0.375 0.905 0.0
Total sample size                    
<600 3 614 568 0.319(0.134-0.761) 0.010 0.982 0.0 0.631(0.401-0.993) 0.047 0.042 68.4 0.659(0.463-0.937) 0.020 0.079 60.5 0.242(0.100-0.583) 0.002 0.955 0.0
≥600 6 2422 4209 0.920(0.772-1.098) 0.357 0.862 0.0 0.920(0.822-1.031) 0.152 0.371 7.1 0.965(0.893-1.043) 0.368 0.964 0.0 0.927(0.761-1.129) 0.452 0.914 0.0
HWE                    
Yes 5 2008 3100 0.859(0.681-1.085) 0.202 0.220 30.3 0.827(0.662-1.033) 0.093 0.005 69.9 0.879(0.736-1.049) 0.152 0.006 69.1 0.832(0.654-1.057) 0.132 0.083 51.5
No 4 1028 1677 0.898(0.695-1.160) 0.409 0.443 0.0 0.833(0.623-1.116) 0.221 0.132 50.7 0.891(0.733-1.083) 0.245 0.173 42.9 0.910(0.662-1.251) 0.563 0.434 0.0