Figure 5From: Ivy gourd (Coccinia grandis L. Voigt) root suppresses adipocyte differentiation in 3T3-L1 cellsProposed molecular mechanisms for the inhibition of adipogenesis by ivy gourd root. The active constituent(s) in ivy gourd root when introduced to 3T3-L1 cells during the induction of differentiation blocks PPARγ and C/EBPα expressions directly leading to a negative regulation of various adipogenic genes, and eventually inhibits adipogenesis in these cells.Back to article page