Table 1 Baseline characteristics according to the tertiles of serum hemoglobin A1C levels

Demographic

Age, years

58.3 ± 10.2

55.5 ± 10.8

59.6 ± 9.6

59.8 ± 9.5

<0.001

Male gender

1008(69.9)

365(75.6)

350(68.3)

293(66.9)

0.008

Risk factors Body mass index (kg/m²)

25.5 ± 3.2

25.0 ± 3.0

25.4 ± 3.3

26.0 ± 3.2

<0.001

Current Smoking

770(53.4)

271(56.1)

272(53.1)

227(51.8)

0.404

Hypertension

909(63.4)

280(58.0)

317(61.9)

312(71.2)

<0.001

Diabetes mellitus

374(26.1)

89(18.4)

93(18.2)

192(43.8)

<0.001

Hyperlipidemia

1064(74.2)

306(63.4)

393(76.8)

365(83.3)

<0.001

Peripheral vascular disease

26(1.8)

6(1.2)

11(2.1)

9(2.1)

0.509

Prior Stroke

68(4.7)

16(3.3)

27(5.3)

25(5.7)

0.182

Family history of CAD

158(11.0)

44(9.1)

55(10.7)

59(13.5)

0.104

Laboratory date

LVEF (%)

62.2 ± 8.1

62.5 ± 8.2

62.1 ± 8.2

62.2 ± 7.9

0.672

NT-pro-BNP (fmol/mL)

710.4 ± 515.7

663.9 ± 422.7

720.8 ± 492.3

749.5 ± 622.1

0.036

FBG (mmol/L)

5.5 ± 1.5

6.8 ± 2.1

5.0 ± 0.6

4.7 ± 0.6

<0.001

Haemoglobin (g/L)

139.9 ± 15.1

141.5 ± 14.9

139.7 ± 14.7

138.3 ± 15.9

0.006

Leucocyte count (10⁹/L)

6.4 ± 1.6

6.2 ± 1.6

6.4 ± 1.6

6.6 ± 1.7

0.002

Platelet count (109/L)

205.1 ± 60.7

201.8 ± 68.6

208.4 ± 58.6

204.9 ± 53.7

0.221

Fibrinogen (g/L)

3.2 ± 0.8

2.9 ± 0.6

3.2 ± 0.7

3.3 ± 0.9

<0.001

D-dimer (mg/dL)

0.4 ± 0.7

0.3 ± 0.4

0.4 ± 0.6

0.3 ± 1.0

0.023

hs-CRP (mg/L)

2.9 ± 3.6

2.1 ± 2.9

3.0 ± 3.5

3.6 ± 4.1

<0.001

Endothelin-1 (fmol/mL)

0.6 ± 0.3

0.6 ± 0.3

0.6 ± 0.3

0.6 ± 0.3

0.492

Albumin (g/L)

41.8 ± 3.5

41.6 ± 3.3

41.9 ± 3.8

41.8 ± 3.4

0.491

Cr (umol/L)

75.6 ± 16.2

75.4 ± 13.8

75.4 ± 17.1

76.2 ± 17.5

0.686

UA (mmol/L)

347.4 ± 4.2

354.0 ± 83.3

348.8 ± 80.5

338.5 ± 88.8

0.017

Lipid profile

Triglycerides (mmol/L)

4.2 ± 1.1

4.1 ± 0.9

4.2 ± 1.1

4.1 ± 1.1

0.008

Total cholesterol (mmol/L)

4.2 ± 1.1

4.0 ± 0.9

4.2 ± 1.1

4.2 ± 1.1

0.077

LDL-C (mmol/L)

2.5 ± 0.9

2.5 ± 0.9

2.5 ± 0.8

2.5 ± 0.9

0.497

HDL-C (mmol/L)

1.1 ± 0.3

1.1 ± 0.3

1.1 ± 0.2

1.1 ± 0.3

0.051

Lipoprotein (a) (mg/L)

236.9 ± 244.6

220.6 ± 224.7

265.6 ± 263.4

221.4 ± 240.4

0.004

ApoA (g/L)

1.5 ± 0.3

1.5 ± 0.3

1.5 ± 0.2

1.5 ± 0.3

0.920

ApoB (g/L)

1.1 ± 0.3

1.0 ± 0.3

1.1 ± 0.3

1.1 ± 0.3

0.157

Medical treatment

Aspirin

1358(94.8)

444(91.9)

490(95.7)

424(96.8)

0.002

Clopidogrel

1297(90.5)

416(86.1)

473(92.4)

408(93.2)

<0.001

Beta-blocker

1129(78.8)

351(72.7)

415(81.1)

363(82.9)

<0.001

ACE-I

424(29.6)

132(27.3)

162(31.6)

130(29.7)

0.389

Statin

1332(93.0)

429(88.8)

486(94.9)

417(95.2)

<0.001

DES implantation

250(17.4)

60(12.4)

109(21.3)

81(18.5)

0.001