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Table 1 Weights, plasma lipids, and non-esterified fatty acids

From: Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction

 

3 months

12 months

 

LF

SFA

SFA + Probucol

LF

SFA

SFA + Probucol

Weight (g)

22.2 ± 0.33

22.7 ± 0.33

22.7 ± 0.33

30.8 ± 1.5

36.4 ± 1.0

32.8 ± 2.5

Weight gain (g)

-

-

-

14.3 ± 1.50

21.3 ± 1.02*

13.26 ± 2.53

Cholesterol (mmol/L)

3.18 ± 0.26

3.13 ± 0.22

0.58 ± 0.074**

3.25 ± 0.29

2.72 ± 0.12

0.58 ± 0.068**

Triglyceride (mmol/L)

0.35 ± 0.023

0.32 ± 0.038

0.44 ± 0.034

0.51 ± 0.082

0.45 ± 0.11

0.56 ± 0.13

NEFA (mEq/L)

0.49 ± 0.064

0.70 ± 0.041**

0.34 ± 0.041

0.47 ± 0.026

0.40 ± 0.021

0.44 ± 0.051

  1. LF = Low fat, SFA = Saturated fatty acid, NEFA = Non-esterified fatty acid.
  2. Data are shown as mean ± SEM. Statistical significance analyzed with one-way ANOVA followed by Tukey’s post hoc test (2 tailed, n = 8) is indicated at p < 0.05 (*) or at p < 0.01 (**).