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Table 3 Multivariate associations of the SNPs with the risk of MI

From: The LRP6 rs2302685 polymorphism is associated with increased risk of myocardial infarction

Type

Controls (n = 650)

Cases (n = 285)

OR (95% CI)a

P-valuea

 

No. (%)

No. (%)

  

LRP6 rs2302685

T

1217 (93.6)

524 (91.9)

1.00

-

C

83 (6.4)

46 (8.1)

1.62 (1.03-2.55)

0.039 b

TT

569 (87.5)

240 (84.2)

1.00

-

CT + CC

81 (12.5)

45 (15.8)

1.67 (1.04-2.67)

0.035

LDLRAP1 rs6687605

C

545 (41.9)

233 (40.9)

1.00

-

T

755 (58.1)

337 (59.1)

1.00 (0.78-1.27)

0.986

CC

104 (16.0)

46 (16.1)

1.00

-

CT + TT

546 (84.0)

239 (83.9)

1.04 (0.67-1.63)

0.854

SOAT1 rs13306731

A

922 (70.9)

403 (70.7)

1.00

-

G

378 (29.1)

167 (29.3)

1.07 (0.83-1.39)

0.584

AA

334 (51.4)

142 (49.8)

1.00

-

GA + GG

316 (48.6)

143 (50.2)

1.04 (0.74-1.44)

0.84

  1. aAdjusted for age, sex, smoking, drinking, hypertension, diabetes and hyperlipidemia.
  2. bP values under 0.05 were indicated in bold font.