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Table 1 Lipid levels in plasma and pancreas of C57 mice at the end of atorvastatin treatment on day 58

From: Atorvastatin helps preserve pancreatic β cell function in obese C57BL/6 J mice and the effect is related to increased pancreas proliferation and amelioration of endoplasmic-reticulum stress

Group

Dose (mg/kg)

TG (mg/dl)

CHO (mg/dl)

Plasma

Pancreas

Plasma

Pancreas

Nor

--

64.3 ± 5.6**

146.0 ± 23.4***

85.3 ± 5.9**

12.5 ± 1.5**

Con

--

140.0 ± 20.7

340.6 ± 7.9

270.2 ± 36.0

18.7 ± 1.8

Ator

30

84.0 ± 8.6*

212.3 ± 19.5***

170.5 ± 9.9*

18.2 ± 1.9

  1. Values are mean ± S.E.M, n = 4-6. *P < 0.05, **P < 0.01, ***P < 0.001 vs. control.