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Table 1 The association between irisin levels and obesity

From: Irisin: a new molecular marker and target in metabolic disorder

 

Population

Group size

Study design

Positive correlation between irisin levels and obesity

Huh et al. [3]

Healthy middle-aged women with wide range of BMI

117

Cross-sectional

Stengel et al. [4]

Anorexia nervosa patients, normal weight control subjects, and morbidly obese patients

40

Cross-sectional

Pardo et al. [5]

Anorexia nervosa patients, normal weight control subjects, and morbidly obese patients

145

Cross-sectional

Liu et al. [6]

Diabetic subjects and non-diabetic subjects

156

Cross-sectional

Huh et al. [3]

Subjects undergoing gastric banding or gastric bypass surgery

14

Interventional

De la Iglesia et al. [13]

Subjects following an 8-week hypocaloric dietary strategy

93

Interventional

Crujeiras et al. [8]

Obese patients undergoing a weight loss program consisting of 8 weeks of a hypocaloric diet and follow-up at 16-weeks

94

Interventional

Negative correlation between irisin levels and obesity

Moreno-Navarrete et al. [10]

Non-diabetic subjects

69

Cross-sectional

Choi et al. [11]

NGT subjects and new-onset T2DM subjects

208

Cross-sectional