Phase angle correlates with n-3 fatty acids and cholesterol in red cells of Nigerian children with sickle cell disease

Table 2 The fatty acid composition of phospholipids from red cells from subjects with SCD and healthy controls (wt%)

Fatty acid	SCD subjects (n = 69)	Control subjects (n =72)	p-value
Saturated
C14:0	0.63 ± 0.21	0.46 ± 0.20	< 0.001
C14:1	0.10 ± 0.07	0.06 ± 0.04	< 0.001
C15:0	0.30 ± 0.17	0.21 ± 0.06	< 0.001
C16:0	30.7 ± 5.03	27.8 ± 2.44	< 0.001
C18:0	16.2 ± 2.80	15.1 ± 2.23	0.003
C20:0	0.22 ± 0.11	0.19 ± 0.06	NS
C22:0	0.22 ± 0.09	0.27 ± 0.09	< 0.001
C24:0	0.28 ± 0.16	0.38 ± 0.18	< 0.001
Monounsaturated
C16:1n-7	1.40 ± 0.67	1.43 ± 0.47	NS
C18:1n-7	2.17 ± 0.53	1.87 ± 0.36	< 0.001
C20: 1n-7	0.08 ± 0.05	0.08 ± 0.04	NS
C18:1n-9	16.5 ± 2.33	15.0 ± 1.56	< 0.001
C20:1n-9	0.34 ± 0.10	0.31 ± 0.08	0.03
C22:1n-9	0.16 ± 0.09	0.19 ± 0.06	< 0.001
C24:1	0.24 ± 0.09	0.26 ± 0.12	NS
Polyunsaturated (n-6)
C18:2n-6	10.7 ± 2.83	14.2 ± 2.41	< 0.001
C20:2n-6	0.33 ± 0.10	0.34 ± 0.08	NS
C18:3n-6	0.11 ± 0.07	0.11 ± 0.05	NS
C20:3n-6	1.44 ± 0.35	1.44 ± 0.24	NS
C20:4n-6	11.9 ± 3.94	13.0 ± 1.97	0.03
C22:4n-6	1.92 ± 0.63	1.61 ± 0.42	NS
(n-3)
C18:3n-3	0.22 ± 0.10	0.22 ± 0.07	NS
C20:5n-3	0.38 ± 0.23	0.64 ± 0.64	<0.001
C22:5n-3	0.91 ± 0.39	1.01 ± 0.24	NS
C22:6n-3	2.36 ± 1.10	3.39 ± 1.07	<0.001

ISSN: 1476-511X