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Table 4 Fecal bile acids and neutral sterols in hamsters treated with G. lucidum and lovastatin (nmol/g dry feces/d)

From: Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs

  Bile acids Neutral Sterols
Group C LC DC CDC UDC Total BA COP-ol COP-3-one CHOL erol CHOL anol Total NS
Control 15.0 14.3 10.7 5.1 1.7 46.7 11.5 ND 7.2 18.4 37.1
Lovastatin 15.0 12.8 11.6 6.2 1.6 47.1 12.0 ND 6.7 18.9 37.6
Gl (2.5%) 16.9 16.2 14.3 8.5a 1.9 57.8a 11.7 4.2a 7.7 16.9 40.6
Gl (5%) 12.2 13.9 12.0 6.4 1.4 45.8 12.0 7.8a 7.0 14.1a 41.0
  1. Feces were collected quantitatively at the conclusion of the experiment (D18). C, cholate; LC, lithocholate; DC, deoxycholate; CDC, chenodeoxycholate, UDC, Ursodeoxycholate; COP, coprostan; CHOL, cholest; BA, bile acids; NS, neutral sterols. ND, not detected. Values represent mean of 6 determinations. aSignificantly different from the control (P < 0.05), students unpaired, 2-tailed t-test, equal variances. No statistical trends (P < 0.10) existed in the data set.