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Table 4 Fecal bile acids and neutral sterols in hamsters treated with G. lucidum and lovastatin (nmol/g dry feces/d)

From: Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs

 

Bile acids

Neutral Sterols

Group

C

LC

DC

CDC

UDC

Total BA

COP-ol

COP-3-one

CHOL erol

CHOL anol

Total NS

Control

15.0

14.3

10.7

5.1

1.7

46.7

11.5

ND

7.2

18.4

37.1

Lovastatin

15.0

12.8

11.6

6.2

1.6

47.1

12.0

ND

6.7

18.9

37.6

Gl (2.5%)

16.9

16.2

14.3

8.5a

1.9

57.8a

11.7

4.2a

7.7

16.9

40.6

Gl (5%)

12.2

13.9

12.0

6.4

1.4

45.8

12.0

7.8a

7.0

14.1a

41.0

  1. Feces were collected quantitatively at the conclusion of the experiment (D18). C, cholate; LC, lithocholate; DC, deoxycholate; CDC, chenodeoxycholate, UDC, Ursodeoxycholate; COP, coprostan; CHOL, cholest; BA, bile acids; NS, neutral sterols. ND, not detected. Values represent mean of 6 determinations. aSignificantly different from the control (P < 0.05), students unpaired, 2-tailed t-test, equal variances. No statistical trends (P < 0.10) existed in the data set.