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Table 2 Serum cholesterol concentration (mmol/L) at baseline and after two 3-week periods of coffee abstention (week 0 – 3 and week 7 – 10) for APOE ε2-positive (n = 13) and APOE ε2-negative (n = 108) individuals

From: The apolipoprotein E polymorphism and the cholesterol-raising effect of coffee

 

APOE ε2-positive

APOE ε2-negative

p

 

n = 13

n = 107/103 a

 

First trial period

   

week 0

4.68 (0.80)

5.28 (0.93)

0.01b

week 3

4.49 (0.71)

5.05 (0.90)

 

diff week 0–3

-0.18 (0.24)

-0.23 (0.55)

0.30 c

p (diff 0–3)

0.02 d

<0.0001d

 

Second trial period

   

week 7

4.52 (0.71)

5.34 (0.93)

 

week 10

4.34 (0.64)

4.95 (0.89)

 

week 7–10

-0.18 (0.41)

-0.39 (0.55)

0.08 c

p (diff 7–10)

0.13

<0.0001d

 
  1. a 107 participants in the first trial period and 103 participants in the second trial period
  2. b Significant difference between APOE ε2-positive and APOE ε2-negative at baseline, Wilcoxon rank sum test
  3. c No significant difference between APOE ε2-positive and APOE ε2-negative in differences between week 0–3 or week 7–10, Wilcoxon rank sum test
  4. d Significant difference between week 0–3 for the APOE ε2-positive group and between week 0–3 and week 7–10 for the APOE ε2-negative group, Signed rank test
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Lipids in Health and Disease

ISSN: 1476-511X