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Table 3 Serum cholesterol concentration (mmol/L) after two 4-week periods of coffee consumption (week 3 – 7 and week 10 – 14) for APOE ε2-positive (n = 13) and APOE ε2-negative (n = 108) individuals

From: The apolipoprotein E polymorphism and the cholesterol-raising effect of coffee

 

APOE ε2-positive

APOE ε2-negative

p

 

n = 13

n = 107/103 a

 

First trial period

   

week 3

4.49 (0.71)

5.05 (0.90)

 

week 7

4.52 (0.71)

5.34 (0.93)

 

diff week 3–7

0.03 (0.57)

0.29 (0.57)

0.09 b

p (diff 3–7)

0.70

<0.0001 c

 

Second trial period

   

week 10

4.34 (0.64)

4.95 (0.89)

 

week 14

4.54 (0.84)

5.09 (0.85)

 

diff week 10–14

0.20 (0.47)

0.14 (0.59)

0.37 b

p (diff 10–14)

0.15

0.009 c

 
  1. a 107 participants in the first trial period and 103 participants in the second trial period
  2. b No significant difference between 2-positive and 2-negative in differences between week 3–7 or week 10–14, Wilcoxon rank sum test
  3. c Significant difference between week 0–3 and week 7–10 for the APOE ε2-negative group, Signed rank test