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Table 3 Serum cholesterol concentration (mmol/L) after two 4-week periods of coffee consumption (week 3 – 7 and week 10 – 14) for APOE ε2-positive (n = 13) and APOE ε2-negative (n = 108) individuals

From: The apolipoprotein E polymorphism and the cholesterol-raising effect of coffee

  APOE ε2-positive APOE ε2-negative p
  n = 13 n = 107/103 a  
First trial period    
week 3 4.49 (0.71) 5.05 (0.90)  
week 7 4.52 (0.71) 5.34 (0.93)  
diff week 3–7 0.03 (0.57) 0.29 (0.57) 0.09 b
p (diff 3–7) 0.70 <0.0001 c  
Second trial period    
week 10 4.34 (0.64) 4.95 (0.89)  
week 14 4.54 (0.84) 5.09 (0.85)  
diff week 10–14 0.20 (0.47) 0.14 (0.59) 0.37 b
p (diff 10–14) 0.15 0.009 c  
  1. a 107 participants in the first trial period and 103 participants in the second trial period
  2. b No significant difference between 2-positive and 2-negative in differences between week 3–7 or week 10–14, Wilcoxon rank sum test
  3. c Significant difference between week 0–3 and week 7–10 for the APOE ε2-negative group, Signed rank test