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Table 2 Rapid effect of L-T4 on phosphatidic acid and phosphatidylinositol contents in the isolated hepatocytes.

From: Effects of thyroxine and 1-methyl, 2-mercaptoimidazol on phosphoinositides synthesis in rat liver

Lipid

Cells:

 

Control

L-T4 -treated

Phosphatidic acid

9,29 ± 0,71

17,7 ± 2,94 *

Phosphatidylinositol

13,6 ± 0,62

13,7 ± 1,83

  1. Hepatocytes were isolated from the liver of adult 90-day-old rats and lipids contents were analyzed as described in "Materials and Methods" and expressed as % of total phospholipids. Hepatocytes were treated with 100 nM NaOH (control) or 10 nM of L-T4 for 30 min. Results are mean ± S.E. of six experiments. * p < 0,05 vs. control.
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Lipids in Health and Disease

ISSN: 1476-511X