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Table 1 Serum triglycerides (TG) and serum total cholesterol (TC) levels in male WT, LPA-YAC transgenic and LPA-YAC/hAPOB transgenic mice

From: Human apoB contributes to increased serum total apo(a) level in LPA transgenic mice

 

AIN-76 diet

HCHF diet

Mice

n

TG (mmol/L)

n

TG (mmol/L)

WT

5

1.8 ± 0.3

5

1.2 ± 0.3

LPA-YAC

4

1.9 ± 0.2

3

2)1.1 ± 0.2

LPA-YAC/hAPOB

6

1)3.1 ± 0.2

8

2)1.4 ± 0.1

Mice

n

TC (mmol/L)

n

TC (mmol/L)

WT

5

5.2 ± 0.4

5

6.3 ± 0.2

LPA-YAC

4

5.3 ± 0.2

3

5.7 ± 0.2

LPA-YAC/hAPOB

6

6.0 ± 0.3

8

3)15.0 ± 0.9

  1. Concentrations are presented as mean ± SEM (mmol/L). 1): Statistically significant difference (P < 0.05) in serum TG levels as compared to the AIN-76 fed WT or LPA-YAC transgenic mice. 2): Statistically significant difference in serum TG levels as compared to the respective AIN-76 fed mice (P < 0.05 for LPA-YAC, P < 0.005 for LPA-YAC/hAPOB). 3): Statistically significant difference (P < 0.005) in serum TC levels as compared to the AIN-76 fed LPA-YAC/hAPOB transgenic mice.