HDL enhances oxidation of LDL in vitro in both men and women

Table 4 Multivariate regression models of factors predicting oxidation parameters in mixtures of LDL and HDL₂.

Dependent variable	Independent variable	Standardized regression coefficient β	p-Value	Total model
LDL + HDL₂
Lag time (min)	fB-Glucose	0.410	0.00037	R² = 0.296
	PI of HDL₂	-0.351	0.00276	p < 0.00005
LDL + HDL₂
Oxidation rate (μmol/ml/min)	ΣPUFA of LDL	0.424	0.0325	R² = 0.57
	ΣPUFA of HDL₂	0.352	0.0129	p < 0.00000
LDL + HDL₂
Maximum diene	HDL₂ 18:2n-6	0.429	0.00015	R² = 0.55
concentration (nmol/mg)	LDL 18:1n-9	-0.292	0.0071	p < 0.00000
	LDL/apoB	0.287	0.0033

Abbreviations: PI, peroxidizability index; ΣPUFA, sum of percentages of polyunsaturated fatty acids; LDL/apoB, the ratio of LDL cholesterol to apoB concentration. Stepwise forward regression analysis

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