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Table 1 Selenium levels in liver (μg/g) and serum (μg/L), GSH-Px levels in liver (μmoles of NADPH oxidized/min/mg protein) after 1 and 2 months of control and high cholesterol diet (HCD) feeding.

From: Hypercholesterolemia and apolipoprotein B expression: Regulation by selenium status

Treatment period Se deficient group Se adequate group Se excess group
  Control Ia HCD Ib Control IIa HCD IIb Control IIIa HCD IIIb
Se in liver       
1 month 1.83 ± 0.26DDD 1.20 ± 0.14***### 3.85 ± 0.29 3.11 ± 0.39** 4.57 ± 0.43LL 2.51 ± 0.29***B
2 months 1.23 ± 0.22DDDAA 0.73 ± 0.05***AAA### 3.97 ± 0.36 2.54 ± 0.27***A 6.51 ± 0.65AAALLL 4.38 ± 0.44***AAABBB
Se in serum       
1 month 1.54 ± 0.15DDD 0.76 ± 0.04***### 2.51 ± 0.24 2.11 ± 0.27* 3.84 ± 0.34LLL 2.62 ± 0.27***BB
2 month 0.98 ± 0.07DDDAAA 0.51 ± 0.02***AAA### 2.82 ± 0.29 1.62 ± 0.17***AA 4.73 ± 0.39AALLL 3.58 ± 0.31***AAABBB
GSH-Px       
1 month 281.45 ± 34.89DDD 354.19 ± 32.79**### 387.42 ± 25.86 467.19 ± 27.66*** 568.82 ± 52.94LLL 686.19 ± 50.58**BBB
2 month 160.33 ± 22.78DDDAAA 463.73 ± 39.91***AAA### 393.16 ± 49.67 593.28 ± 35.38***AAA 672.91 ± 58.16AALLL 825.16 ± 63.85**AABBB
  1. Data is represented as mean ± SD from 6 observations.
  2. *p<0.05, **p<0.01, ***p<0.001 represent comparison between control and HCD groups; Ap<0.05, AAp<0.01, AAAp<0.001 comparison between 1 and 2 months; DDDp<0.001 comparison between group Ia and IIa; ###p<0.001 comparison between group Ib and IIb; LLp<0.01, LLLp<0.001 comparison between group IIa and IIIa; Bp<0.05, BBp<0.01, BBBp<0.001 comparison between group IIb and IIIb.