From: Hypercholesterolemia and apolipoprotein B expression: Regulation by selenium status
Treatment period | Se deficient group | Se adequate group | Se excess group | |||
---|---|---|---|---|---|---|
 | Control Ia | HCD Ib | Control IIa | HCD IIb | Control IIIa | HCD IIIb |
Se in liver | Â | Â | Â | Â | Â | Â |
1 month | 1.83 ± 0.26DDD | 1.20 ± 0.14***### | 3.85 ± 0.29 | 3.11 ± 0.39** | 4.57 ± 0.43LL | 2.51 ± 0.29***B |
2 months | 1.23 ± 0.22DDDAA | 0.73 ± 0.05***AAA### | 3.97 ± 0.36 | 2.54 ± 0.27***A | 6.51 ± 0.65AAALLL | 4.38 ± 0.44***AAABBB |
Se in serum | Â | Â | Â | Â | Â | Â |
1 month | 1.54 ± 0.15DDD | 0.76 ± 0.04***### | 2.51 ± 0.24 | 2.11 ± 0.27* | 3.84 ± 0.34LLL | 2.62 ± 0.27***BB |
2 month | 0.98 ± 0.07DDDAAA | 0.51 ± 0.02***AAA### | 2.82 ± 0.29 | 1.62 ± 0.17***AA | 4.73 ± 0.39AALLL | 3.58 ± 0.31***AAABBB |
GSH-Px | Â | Â | Â | Â | Â | Â |
1 month | 281.45 ± 34.89DDD | 354.19 ± 32.79**### | 387.42 ± 25.86 | 467.19 ± 27.66*** | 568.82 ± 52.94LLL | 686.19 ± 50.58**BBB |
2 month | 160.33 ± 22.78DDDAAA | 463.73 ± 39.91***AAA### | 393.16 ± 49.67 | 593.28 ± 35.38***AAA | 672.91 ± 58.16AALLL | 825.16 ± 63.85**AABBB |