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Table 2 Erythrocyte fatty acid profile in 20 healthy men following 21 days on a high saturated or a high unsaturated fat diet

From: Assessment of erythrocyte phospholipid fatty acid composition as a biomarker for dietary MUFA, PUFA or saturated fatty acid intake in a controlled cross-over intervention trial

 

High SFA (% peak area)

High USFA (% peak area)

SFA profile

  

   C10:0 Capric acid

nd

nd

   C12:0 Lauric acid

0.36 ± 0.22

0.39 ± 0.23

   C14:0 Myristic acid

0.54 ± 0.07

0.49 ± 0.05***

   C15:0 Pentadecanoic acid

0.20 ± 0.15

0.17 ± 0.14

   C16:0 Palmitic acid

26.27 ± 0.97

25.26 ± 0.89***

   C17:0 Heptadecanoic acid

0.48 ± 0.12

0.50 ± 0.12

   C18:0 Stearic acid

9.67 ± 0.91

10.31 ± 0.95**

   Total SFA

37.5

37.1

MUFA profile

  

   C16:1n-7 Palmitoleic acid

nd

nd

   C18:1n-9 Oleic acid

10.25 ± 0.82

10.70 ± 0.88**

   Total MUFA

10.3

10.7

PUFA profile

  

   C18:2n-6 Linoleic acid [LA]

15.25 ± 1.65

14.99 ± 1.77

   C18:3n-3 α-Linolenic acid [ALA]

0.4 ± 0.2

0.4 ± 0.2

   C20:4n-6 Arachidonic acid [AA]

10.17 ± 1.01

10.6 ± 0.88**

   C20:5n-3 Eicosapentaenoic acid [EPA]

0.62 ± 0.13

0.56 ± 0.24

   C22:4n-6 Docosatetraenoic acid

1.90 ± 0.42

1.99 ± 0.58

   C22:6n-3 Docosahexaenoic acid [DHA]

2.77 ± 0.51

2.82 ± 0.53

   Total PUFA

27.7

31.4

  1. SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid. % peak area calculated from fatty acid methyl esters (FAMEs). Minor fractions of fatty acid profiles not shown. Significantly different from high SFA diet: *P < 0.05, ** P < 0.01, ***P < 0.001, nd, not detectable. Mean ± sd