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Table 2 Erythrocyte fatty acid profile in 20 healthy men following 21 days on a high saturated or a high unsaturated fat diet

From: Assessment of erythrocyte phospholipid fatty acid composition as a biomarker for dietary MUFA, PUFA or saturated fatty acid intake in a controlled cross-over intervention trial

  High SFA (% peak area) High USFA (% peak area)
SFA profile   
   C10:0 Capric acid nd nd
   C12:0 Lauric acid 0.36 ± 0.22 0.39 ± 0.23
   C14:0 Myristic acid 0.54 ± 0.07 0.49 ± 0.05***
   C15:0 Pentadecanoic acid 0.20 ± 0.15 0.17 ± 0.14
   C16:0 Palmitic acid 26.27 ± 0.97 25.26 ± 0.89***
   C17:0 Heptadecanoic acid 0.48 ± 0.12 0.50 ± 0.12
   C18:0 Stearic acid 9.67 ± 0.91 10.31 ± 0.95**
   Total SFA 37.5 37.1
MUFA profile   
   C16:1n-7 Palmitoleic acid nd nd
   C18:1n-9 Oleic acid 10.25 ± 0.82 10.70 ± 0.88**
   Total MUFA 10.3 10.7
PUFA profile   
   C18:2n-6 Linoleic acid [LA] 15.25 ± 1.65 14.99 ± 1.77
   C18:3n-3 α-Linolenic acid [ALA] 0.4 ± 0.2 0.4 ± 0.2
   C20:4n-6 Arachidonic acid [AA] 10.17 ± 1.01 10.6 ± 0.88**
   C20:5n-3 Eicosapentaenoic acid [EPA] 0.62 ± 0.13 0.56 ± 0.24
   C22:4n-6 Docosatetraenoic acid 1.90 ± 0.42 1.99 ± 0.58
   C22:6n-3 Docosahexaenoic acid [DHA] 2.77 ± 0.51 2.82 ± 0.53
   Total PUFA 27.7 31.4
  1. SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid. % peak area calculated from fatty acid methyl esters (FAMEs). Minor fractions of fatty acid profiles not shown. Significantly different from high SFA diet: *P < 0.05, ** P < 0.01, ***P < 0.001, nd, not detectable. Mean ± sd