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Table 3 Baseline plasma cholesterol and triglycerides and estimated percent changes after 12 months when using PI among 679 subjects treated for HIV/AIDS at St Paul's Hospital, Vancouver, BC, August 1996 – January 2002

From: Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS

 

Number of measurements (subjects)

Mean lipid baseline measurements (SD)

% change* (95% CI)

TChol

1620 (529)

4.2 (1.0)

20 (17, 24)

HDL

1250 (419)

1.0 (0.3)

22 (15, 29)

LDL

677 (295)

2.5 (0.8)

12 (5, 20)

N-HDL

1247 (419)

3.1 (1.2)

20 (15, 26)

TRG

1743 (556)

1.9 (1.2)

22 (12, 33)

  1. Abbreviations: PI protease inhibitor; TChol = total cholesterol; HDL = high-density lipoprotein cholesterol; LDL = low- density lipoprotein cholesterol; N-HDL = Non-HDL Cholesterol; TRG = triglycerides
  2. * Adjusted for age, sex, and CD4+ cell count at first prescription for HAART, concomitant use of non-nucleoside reverse transcriptase inhibitor and adherence to antiretroviral therapy in the first year of treatment