Table 3 Mechanisms mediating the anti-atherosclerotic effect of nitric oxide
Anti-atherosclerotic effect of nitric oxide | Reference(s) |
|---|---|
Promotion of SMC proliferation | 131 |
Inhibition of platelet aggregation | 132 |
Reduction in endothelial activation & Inhibition of MCP-1 | 133, 134 |
Stabilizes NF-Kβ inhibitor, Ikβα | 135 |
Inhibition of LDL oxidation & lipid peroxidation | 136,137 |
Reduces super oxide generation | 138 |
Decrease the Expression of PAI-1 | 34 |
Nitric oxide regulates vascular cell adhesion molecule 1 gene expression | 139 |