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Table 3 Mechanisms mediating the anti-atherosclerotic effect of nitric oxide

From: Mining literature for a comprehensive pathway analysis: A case study for retrieval of homocysteine related genes for genetic and epigenetic studies

Anti-atherosclerotic effect of nitric oxide Reference(s)
Promotion of SMC proliferation 131
Inhibition of platelet aggregation 132
Reduction in endothelial activation & Inhibition of MCP-1 133, 134
Stabilizes NF-Kβ inhibitor, Ikβα 135
Inhibition of LDL oxidation & lipid peroxidation 136,137
Reduces super oxide generation 138
Decrease the Expression of PAI-1 34
Nitric oxide regulates vascular cell adhesion molecule 1 gene expression 139