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Table 1 Influence of Caloric Restriction and Re-feeding on Plasma Metabolites in B6 Micea

From: Caloric restriction in C57BL/6J mice mimics therapeutic fasting in humans

Metabolites UR R Difference(%) R-RF Fd(2,9)
Glucoseb 15.5 ± 0.86 9.1 ± 1.83** 41 12.5 ± 1.61* 18.3
β-hydroxybutyrateb 0.3 ± 0.12 1.4 ± 0.13** 367 0.3 ± 0.05 141.4
Neutral lipids c      
Triglycerides 2.4 ± 0.63 1.0 ± 0.16* -58 2.5 ± 1.00 6.1
Cholesterol 0.5 ± 0.23 0.2 ± 0.06* -60 0.4 ± 0.14 3.7
Phosphatidylcholine 2.8 ± 0.53 1.7 ± 0.25** -39 2.8 ± 0.30 10.3
Acidic Lipids c      
Fatty acids 0.3 ± 0.08 0.8 ± 0.05** 167 0.3 ± 0.05 69.7
Phosphatidylinositol 0.2 ± 0.03 0.2 ± 0.01 0 0.2 ± 0.03 1.2
  1. a Values represent the mean ± 95% CI. Four independent samples were analyzed per group.
  2. b Values are expressed as mM.
  3. c Determined from densitometric scanning of HPTLC as shown in Figures 3 and 4. Values are expressed as mg lipid/ml plasma.
  4. d /F/ ratio and degree of freedom (df) obtained from one way analysis of variance.
  5. Astericks indicate that the value is significantly different from that of the control at the * p < 0.05 and ** p < 0.01 as determined by ANOVA followed by Fisher's PLSD