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Table 4 Plasma lipid concentrations in the combined hyperlipidemia subjects, grouped by LPL genotype.

From: The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion

  

SS (n = 199)

SX + XX (n = 13)

p-value

Age

 

53.3 ± 12.28 (198)

51.7 ± 8.70 (13)

0.647

BMI

 

27.6 ± 4.60 (145)

29.6 ± 3.21 (9)

0.216

TG*

Total

383.8 ± 357.69 (199)

267.2 ± 65.24 (13)

0.099

 

VLDL

281.7 ± 262.98 (199)

184.6 ± 62.40 (13)

0.060

 

LDL

76.3 ± 183.55 (199)

59.4 ± 24.22 (13)

0.809

 

HDL

21.7 ± 8.72 (199)

21.9 ± 19.84 (13)

0.075

C*

Total

295.5 ± 73.96 (199)

269.2 ± 48.10 (13)

0.264

 

VLDL

70.4 ± 59.29 (199)

48.4 ± 21.43 (13)

0.045

 

LDL

180.8 ± 56.74 (199)

175.3 ± 43.55 (13)

0.926

 

HDL

40.4 ± 11.87 (199)

43.7 ± 20.09 (13)

0.661

TG/HDLC

11.70 ± 18.07 (199)

7.82 ± 5.849 (13)

0.153

  1. * Lipid measurements expressed in mg/dL. All test statistics are non-parametric (Wilcoxon two sample test).
  2. TC, total cholesterol; TG, triglyceride; VLDL-C, very low density lipoprotein – cholesterol; LDL-C, low density lipoprotein-cholesterol; HDL, high density lipoprotein; BMI, body mass index; SS, individuals homozygous for the Ser447 allele; SX+XX, individuals that carry either one or two 447X alleles.