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Table 4 Plasma lipid concentrations in the combined hyperlipidemia subjects, grouped by LPL genotype.

From: The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion

   SS (n = 199) SX + XX (n = 13) p-value
Age   53.3 ± 12.28 (198) 51.7 ± 8.70 (13) 0.647
BMI   27.6 ± 4.60 (145) 29.6 ± 3.21 (9) 0.216
TG* Total 383.8 ± 357.69 (199) 267.2 ± 65.24 (13) 0.099
  VLDL 281.7 ± 262.98 (199) 184.6 ± 62.40 (13) 0.060
  LDL 76.3 ± 183.55 (199) 59.4 ± 24.22 (13) 0.809
  HDL 21.7 ± 8.72 (199) 21.9 ± 19.84 (13) 0.075
C* Total 295.5 ± 73.96 (199) 269.2 ± 48.10 (13) 0.264
  VLDL 70.4 ± 59.29 (199) 48.4 ± 21.43 (13) 0.045
  LDL 180.8 ± 56.74 (199) 175.3 ± 43.55 (13) 0.926
  HDL 40.4 ± 11.87 (199) 43.7 ± 20.09 (13) 0.661
TG/HDLC 11.70 ± 18.07 (199) 7.82 ± 5.849 (13) 0.153
  1. * Lipid measurements expressed in mg/dL. All test statistics are non-parametric (Wilcoxon two sample test).
  2. TC, total cholesterol; TG, triglyceride; VLDL-C, very low density lipoprotein – cholesterol; LDL-C, low density lipoprotein-cholesterol; HDL, high density lipoprotein; BMI, body mass index; SS, individuals homozygous for the Ser447 allele; SX+XX, individuals that carry either one or two 447X alleles.