Figure 2From: Accumulation of low density lipoprotein associated cholesterol in calcifying vesicle fractions correlates with intimal thickening in thoracic aortas of juvenile rabbits fed a supplemental cholesterol dietThe cholesterol content in various subcellular fractions correlates well with intimal thickening despite the use of limited numbers of rabbits. The cholesterol content in each fraction was run manually using a commercial kit (Thermo DMA Inc.). (A) The cholesterol content in calcifying vesicle fractions; r2 = 0.98, p < 0.0001. (B) The cholesterol content in microsomal fractions; r2 = 0.52, p = 0.0036. (C) The cholesterol content in supernatant fractions, r2 = 0.45, p = 0.009. The content of cholesterol in each fraction was expressed as μg cholesterol/cm of aorta. Fourteen rabbits were fed the cholesterol supplemental diet while 9 rabbits were fed chow diets.Back to article page