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Figure 2 | Lipids in Health and Disease

Figure 2

From: Accumulation of low density lipoprotein associated cholesterol in calcifying vesicle fractions correlates with intimal thickening in thoracic aortas of juvenile rabbits fed a supplemental cholesterol diet

Figure 2

The cholesterol content in various subcellular fractions correlates well with intimal thickening despite the use of limited numbers of rabbits. The cholesterol content in each fraction was run manually using a commercial kit (Thermo DMA Inc.). (A) The cholesterol content in calcifying vesicle fractions; r2 = 0.98, p < 0.0001. (B) The cholesterol content in microsomal fractions; r2 = 0.52, p = 0.0036. (C) The cholesterol content in supernatant fractions, r2 = 0.45, p = 0.009. The content of cholesterol in each fraction was expressed as μg cholesterol/cm of aorta. Fourteen rabbits were fed the cholesterol supplemental diet while 9 rabbits were fed chow diets.

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