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Table 1 Terminal plasma leptin and perigenital fat pad weights

From: Improved glucose tolerance in acyl CoA:diacylglycerol acyltransferase 1-null mice is dependent on diet

 

Males

Females

 

+/+

+/-

-/-

+/+

+/-

-/-

Chow diet:

      

Leptin (ng/ml)

2.2 ± 1.8

4.4 ± 1.8***

1.5 ± 0.4

5.5 ± 3.7

4.2 ± 2.4

1.9 ± 0.2

Fat pad weight (g)

0.50 ± 0.07

0.78 ± 0.11*

0.32 ± 0.03***

0.70 ± 0.08

0.56 ± 0.08

0.31 ± 0.05***

High fat diet:

      

Leptin (ng/ml)

16.3 ± 2.1

16.0 ± 2.4

1.2 ± 0.3***

21.1 ± 1.5

19.6 ± 2.2

2.8 ± 0.3***

Fat pad weight (g)

1.57 ± 0.13

1.52 ± 0.7

0.32 ± 0.04***

1.67 ± 0.18

1.31 ± 0.15

0.48 ± 0.14***

  1. Values are means ± S.E. of 10 to 12 values, except that there were 5 values for plasma leptin and 6 for fat pad weight for the female Dgat1-/- mice fed on the high fat diet.
  2. * P < 0.05; *** P < 0.001 compared to wildtype mice of the same sex.
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Lipids in Health and Disease

ISSN: 1476-511X