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Table 2 Genes involved in inflammatory response that were differentially expressed in subjects with obesity and type 2 diabetes mellitus.

From: Gene expression profile in obesity and type 2 diabetes mellitus

Condition Differentially expressed genes concerned with inflammation
Diabetic with family history vs Healthy individual (DPH vs H) ALK, GCH1, IFIH1, IFIT1, IL11RA, ITGB2,MAP3K4, MMP19, MMP3, RPS27A, SLK, TNFRSF12A, UBC
Diabetic without family history vs healthy individual (DNPH1 vs H) CCL3, CDKN1A, CXCL12, HLA-A, IL11RA, KRT8, LTB, MAP3K4, MMP10, MMP19, MMP20, MMP3, RPS27A, TNFSF10, UBC
Diabetic without family history Vs healthy individual (DNPH2 vs H) CCL16, CCR8, CXCL11, CXCL12, FN1, GCH1, HLA-A, IL11RA, LTB, MMP19, MMP3, RHOA, S100A12, SLK, SYK, UBC
Obese vs Healthy (O vs H) CCL13, CXCL12, HLA-A, IL6, KRT8, MMP19, MMP27, MMP3, RPS27A, UBC
Diabetic with family history vs obesity (DPH vs O) ALK, CCL13, CCR4, CCR8, HGF, HLA-A, IFIT1, IL20, IL6, IL8RA, ITGB2, KRT8, MC1R, MMP20, MMP27, SLK, TNFRSF12A, UBC
Obese individual vs individual who is overweight (O vs HO) CCL13, CCL16, CCR8, HLA-A, IFIT1, IL6, KRT8, MC1R, MMP16, MMP27, TNFRSF12A, UBC
Diabetic with family history vs Diabetic without family history (DPH vs DNPH1) ALK, CCL13, CCR8, CDKN1A, EDN1, FGF1, IFIT1, IL12RB1, IL20, IL22, IL2RG, IL8RA, ITGB2, MMP20, SLK, TNFRSF12A, UBC, XCR1
Diabetic with family history vs Diabetic without family History2 (DPH vs DNPH2) ALK, BLR1, CCL15, CCL16, CCR7, CCR8, CXCL11, CXCL12, FN1, FTH1, GBP1, HLA-A, IFIT1, IL12A, ITGB2, KIT, LTB, MMP20, PPARD, RHOA, RPS27A, TAC1, TLR4, TNFAIP6, TNFRSF11A