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Table 6 Effect of the CORE and CQR-300 on blood lipids and fasting blood glucose

From: The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress

  Group 1 BMI>30 Placebo (2100 Kcal/day diet) Group 2 BMI>30 CORE (no dietary restriction) Group 3 BMI>30 CORE (2100 Kcal/day diet) Group 4 BMI>30 CQR-300 (2100 Kcal/day diet) Group 5 BMI 24–29.9 CORE (no dietary restriction)
Time (weeks) T = 0 T = 6 T = 0 T = 8 T = 0 T = 8 T = 0 T = 6 T = 0 T = 8
Total Cholesterol (mg/dL) 136.3 ± 9.0 138.3 ± 11.1 159.1 ± 14.6 116.2 ± 9.7* 171.0 ± 15.9 126.5 ± 7.9 * 138.3 ± 13.8 113.4 ± 4.5* 152.6 ± 8.8 123.0 ± 4.7*
LDL-cholesterol (mg/dL) 88.4 ± 5.9 88.2 ± 5.9 99.8 ± 6.5 81.4 ± 1.7 116.6 ± 5.4 78.8 ± 3.3 92.7 ± 7.0 65.8 ± 3.4 101.6 ± 1.9 74.8 ± 0.9
HDL-cholesterol (mg/dL) 27.3 ± 2.2 25.8 ± 3.1 36.6 ± 4.7 55.1 ± 6.4* 38.6 ± 10.5 55.2 ± 8.6* 25.6 ± 4.8 31.0 ± 3.9 44.4 ± 7.7 52.0 ± 8.1
Triacylglycerol (mg/dL) 93.6 ± 4.8 90.5 ± 10.4 156.0 ± 16.8 95.6 ± 8.1 144.9 ± 43.3 104.3 ± 26.2* 93.8 ± 9.7 73.4 ± 6.0*** 117.4 ± 9.8 99.8 ± 11.2
Fasting Blood glucose (mg/dL) 93.6 ± 7.2 89.4 ± 10.1 101.3 ± 8.6 87.7 ± 10.0 102.4 ± 1.8 85.9 ± 5.2 91.8 ± 6.9 78.4 ± 11.2 93.3 ± 10.2 82.7 ± 7.2
  1. Values are means ± SE, comparing starting point to end point, significant differences were at *p < 0.05, **p < 0.01 and ***p < 0.001 for the same treatment.