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Table 6 Effect of the CORE and CQR-300 on blood lipids and fasting blood glucose

From: The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress

 

Group 1

BMI>30

Placebo

(2100 Kcal/day diet)

Group 2

BMI>30

CORE

(no dietary restriction)

Group 3

BMI>30

CORE

(2100 Kcal/day diet)

Group 4

BMI>30

CQR-300

(2100 Kcal/day diet)

Group 5

BMI 24–29.9

CORE

(no dietary restriction)

Time (weeks)

T = 0

T = 6

T = 0

T = 8

T = 0

T = 8

T = 0

T = 6

T = 0

T = 8

Total Cholesterol (mg/dL)

136.3 ± 9.0

138.3 ± 11.1

159.1 ± 14.6

116.2 ± 9.7*

171.0 ± 15.9

126.5 ± 7.9 *†

138.3 ± 13.8

113.4 ± 4.5*

152.6 ± 8.8

123.0 ± 4.7*

LDL-cholesterol (mg/dL)

88.4 ± 5.9

88.2 ± 5.9

99.8 ± 6.5

81.4 ± 1.7

116.6 ± 5.4

78.8 ± 3.3

92.7 ± 7.0

65.8 ± 3.4

101.6 ± 1.9

74.8 ± 0.9

HDL-cholesterol (mg/dL)

27.3 ± 2.2

25.8 ± 3.1

36.6 ± 4.7

55.1 ± 6.4*

38.6 ± 10.5

55.2 ± 8.6*†

25.6 ± 4.8

31.0 ± 3.9

44.4 ± 7.7

52.0 ± 8.1

Triacylglycerol (mg/dL)

93.6 ± 4.8

90.5 ± 10.4

156.0 ± 16.8

95.6 ± 8.1

144.9 ± 43.3

104.3 ± 26.2*†

93.8 ± 9.7

73.4 ± 6.0***

117.4 ± 9.8

99.8 ± 11.2

Fasting Blood glucose (mg/dL)

93.6 ± 7.2

89.4 ± 10.1

101.3 ± 8.6

87.7 ± 10.0

102.4 ± 1.8

85.9 ± 5.2

91.8 ± 6.9

78.4 ± 11.2

93.3 ± 10.2

82.7 ± 7.2

  1. Values are means ± SE, comparing starting point to end point, significant differences were at *p < 0.05, **p < 0.01 and ***p < 0.001 for the same treatment.