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Figure 4 | Lipids in Health and Disease

Figure 4

From: Feeding oxidized fat during pregnancy up-regulates expression of PPARα-responsive genes in the liver of rat fetuses

Figure 4

Effects of treatment on relative mRNA concentrations of proto-oncogenes in livers of pregnant rats and fetuses. Effect of short-term (d 16 – d 21 of pregnancy, left) and long-term (d 1 – d 21 of pregnancy, right) administration of three different diets (control, oxidized fat, clofibrate) during pregnancy on relative mRNA concentrations of c-myc, c-jun, and c-fos in the liver of pregnant rats and fetuses at d 21 of pregnancy. Left, Bars represent mean ± SD (n = 9/group). Right, Bars represent mean ± SD (n = 12/group). Bars marked without a common superscript letter differ (P < 0.05). Results from one-way ANOVA (P-values): short-term experiment: c-myc, P = 0.880 (pregnant), P = 0.807 (fetus); c-jun, P = 0.362 (pregnant), P = 0.552 (fetus); c-fos, P = 0.669 (pregnant), P = 0.966 (fetus); long-term experiment: c-myc, P = 0.001 (pregnant), P = 0.420 (fetus); c-jun, P = 0.0001 (pregnant), P = 0.086 (fetus); c-fos, P = 0.048 (pregnant), P = 0.323 (fetus).

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