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Table 1 Possible cumulative impact of four secondary prevention treatments in the prevention of cardiovascular diseases.

From: Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules

Drug therapy

Relative-risk reduction

2-year event ratio

None

-

8%

Aspirin

25%

6%

B-blockers

25%

4.5%

Lipid lowering (by 1–5 mmol)

30%

3.0%

ACE inhibitors

25%

2.3%

  1. Cumulative relative reduction if all four drugs are used is about 75% [see ref. [91]].
  2. Events that were included in this analysis are: cardiovascular death, myocardial infarction or strokes.
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Lipids in Health and Disease

ISSN: 1476-511X