Effects on hemodynamics and gas exchange of omega-3 fatty acid-enriched lipid emulsion in acute respiratory distress syndrome (ARDS): a prospective, randomized, double-blind, parallel group study

Table 2 Hemodynamic parameters

	T-0 h (baseline, preinfusion)	T-6 h	T-12 h (final infusion)	T-18 h (6 h postinfusion)
HR
A: n-3	91 ± 19	101 ± 20	100 ± 21	91 ± 25
B: LCT	95 ± 13	93 ± 12	95 ± 12	84 ± 16
CO
A: n-3	7.8 ± 2.8	8.4 ± 2.7	8.5 ± 2.7	7.8 ± 3
B: LCT	6.9 ± 1.3	7.3 ± 1.9	6.8 ± 1.6	6.1 ± 1.3
SAP
A: n-3	127 ± 19	113 ± 14	117 ± 15	131 ± 24
B: LCT	126 ± 9	126 ± 10	124 ± 14	121 ± 14
MPAP
A: n-3	26 ± 5	29 ± 4	28 ± 7	28 ± 6
B: LCT	30 ± 7	31 ± 7	31 ± 6	28 ± 7
PW
A: n-3	13 ± 4*	13 ± 2	14 ± 3	14 ± 4
B: LCT	16 ± 2	17 ± 2	17 ± 2	16 ± 2
PVR
A: n-3	162 ± 122	187 ± 98	155 ± 68	162 ± 92
B: LCT	147 ± 84	142 ± 102	138 ± 79	134 ± 77
SVR
A: n-3	822 ± 328	644 ± 194	629 ± 228	864 ± 376
B: LCT	863 ± 217	840 ± 274	884 ± 298	932 ± 238
DO ₂
A: n-3	1074 ± 340	1171 ± 406	1174 ± 372	1066 ± 518
B: LCT	966 ± 224	1023 ± 330	936 ± 227	856 ± 225
VO ₂ /DO ₂
A: n-3	0.22 ± 0.04	0.24 ± 0.05	0.23 ± 0.04	0.25 ± 0.06
B: LCT	0.26 ± 0.05	0.25 ± 0.04	0.27 ± 0.03	0.25 ± 0.04
Q _s /Q _t
A: n-3	33 ± 10	31 ± 8	33 ± 11	28 ± 7
B: LCT	28 ± 11	27 ± 6	25 ± 8	25 ± 9
BT
A: n-3	38.1 ± 1	38 ± 0.9	38.1 ± 0.8	37.6 ± 1.2
B: LCT	37.6 ± 0.4	37.5 ± 0.6	37.6 ± 0.4	37.1 ± 1

HR: heart rate, CO: cardiac output, SAP: systolic artery pressure, MPAP: mean pulmonary artery pressure, PW: pulmonary artery occlusion pressure, PVR: pulmonary vascular resistances, SVR: systemic vascular resistances DO₂: oxygen delivery, Q_s/Q_t: venous admixture ratio, BT: body temperature.
* p < 0.05 between baseline groups

ISSN: 1476-511X