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Table 1 Effect of IGOB131 on the inhibition of Intracellular Triglycerides and G3PDH activity in 3T3-l1 adipocytes.

From: Inhibition of Irvingia gabonensis seed extract (OB131) on adipogenesis as mediated via down regulation of the PPARgamma and Leptin genes and up-regulation of the adiponectin gene

Compound

% Intracellular Triglyceride Inhibition*

% Intracellular G3PDH Inhibition

IGOB131

80.9 ± 0.7

71.6 ± 1.2

  1. *Inhibitions (%) are expressed as percentages of the inhibition of control at 0%. 3T3-L1 adipocytes were harvested 8 days after the initiation of differentiation. The cells were incubated with 250 μM of IGOB131 for 72 h at 37°C in 5% CO2 incubator. The reported values are the means ± SD (n = 3).