Apolipoprotein gene polymorphisms and plasma levels in healthy Tunisians and patients with coronary artery disease

Table 1 Allele and genotype frequencies of APO (a) (PNR), APO E, APO CI and APO CII in control and CAD groups.

Allele	Allele frequencies		Genotype	Genotype Frequencies
	Control (N = 100)	CAD (N = 80)		Control (N = 100)	CAD (N = 80)
APO (a)
*7	0.145	0.168	7/7	0.020	0.020
*8	0.645	0.650	7/8	0.210	0.240
*9	0.100	0.037	8/8	0.430	0.400
*10	0.045	0.087	8/9	0.110	0.040
*11	0.065	0.056	8/10	0.040	0.100
			8/11	0.070	0.120
			9/10	0.020	0.020
			Others	0.100	0.060
P	0.276			0.182
APO E
*E2	0.045	0.037	E2/E2	-	-
*E3	0.870	0.876	E2/E3	0.080	0.080
*E4	0.085	0.087	E2/E4	0.010	-
			E3/E3	0.780	0.760
			E3/E4	0.130	0.160
			E4/E4	-	-
P	0.917			0.835
APO CI
*H1	0.915	0.893	H1/H1	0.830	0.820
*H2	0.085	0.107	H1/H2	0.170	0.180
P	1			1
APO CII
*A1	0.555	0.512	A1/A1	0.310	0.320
*A2	0.445	0.488	A1/A2	0.490	0.400
			A2/A2	0.200	0.280
P	0.618			0.635

Alleles (*H1, *A1) and (*H2, *A2) indicate absence and presence, respectively, of the enzyme restriction site.
P: Probability values for the comparison of allele and genotype frequencies between controls and CAD.

ISSN: 1476-511X