Figure 4
Effect of leptin infusion on activities of enzymes related to lipid metabolism in the liver of diet-induced lipodystrophy model mice. Mice were fed normal or lipodystrophy model diets for 4 weeks and were infused intrapeneally 0 or 5 μ g of leptin per day for the final week of the 4-week feeding period. Values are expressed as mean ± SE. a, bDifferent letters show significant differences at P < 0.05. FAS, fatty acid synthase; ME, malic enzyme; PAP, phosphatidate phosphohydrolase.