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Figure 2 | Lipids in Health and Disease

Figure 2

From: Macrophage cholesterol efflux correlates with lipoprotein subclass distribution and risk of obstructive coronary artery disease in patients undergoing coronary angiography

Figure 2

Correlation of cholesterol efflux to HDL2 (top left) and apoA-I (bottom left) with concentration of lipoprotein particles in various subclasses as determined by NMR-spectroscopy of lipids. For size definition of individual lipoprotein particles see Table 1. Correlation is expressed as Spearman's correlation coefficient (r) = y-axis with the level of significance indicated for each p < 0.01. Correlation of macrophage cholesterol efflux from patient derived macrophages onto exogenously added HDL2 (20 microgramm/ml; top right) and apoA-I (10 microgramm/ml; bottom right) with concentration of HDL [A] particles in nmol/l (HDL [A] = smallest subclass of HDL particles as defined by NMR with a size of 7 to 8.5 nm). Cholesterol efflux is expressed as % of total cellular radioactivity released into the medium after 24 hours incubation.

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Lipids in Health and Disease

ISSN: 1476-511X