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Figure 2 | Lipids in Health and Disease

Figure 2

From: Mclk1+/- mice are not resistant to the development of atherosclerosis

Figure 2

Heterozygosity for Mclk1 does not prevent atherosclerosis in the ApoE-/- disease model. Atherosclerotic lesions that stain with the lipid-sensitive dye Oil Red O were quantified on the inner surface of the aorta in ApoE-/- mice at (A) 10 months, initial trial with four backcrosses into C57BL/6J, (B) 10 months, second trial with ten backcrosses into C57BL/6J and (C) 18 months, with three backcrosses into C57BL/6J. F and M labels stand for females and males, respectively. The +/+ and +/- labels stand for the Mclk1+/+ and Mclk1+/- genotypes, respectively.

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