Table 2 Plasma lipid characteristics and body weight at sacrifice (expressed as mean ± standard deviation)
From: Mclk1+/- mice are not resistant to the development of atherosclerosis
| Â | Age | Sex | Mclk1 | Cholesterol (mg/dl) | Triglycerides (mg/dl) | TBARS (nmol MDA/ml) | Weight (g) |
|---|---|---|---|---|---|---|---|
ApoE -/- | 10 months (1) | F | +/+ | 501 ± 120 | 89 ± 28 | 33 ± 23 | 23.7 ± 2.8 |
|  |  |  | +/- | 540 ± 97 | 109 ± 45 | 38 ± 12 | 25.4 ± 3.7 |
|  |  | M | +/+ | 529 ± 199 | 162 ± 51 * | 42 ± 33 | 32 ± 3.5 |
|  |  |  | +/- | 454 ± 166 | 118 ± 47 * | 23 ± 16 | 31.2 ± 2.3 |
|  | 10 months (2) | F | +/+ | 337 ± 78 | 67 ± 20 | 8.6 ± 2.4 | 21.9 ± 1.5 |
|  |  |  | +/- | 362 ± 67 | 63 ± 18 | 7.9 ± 2.4 | 21.6 ± 1.5 |
|  |  | M | +/+ | 267 ± 94 * | 82 ± 27 | 9.4 ± 4.9 | 28.2 ± 1.8 |
|  |  |  | +/- | 351 ± 112 * | 83 ± 22 | 10.2 ± 6.3 | 27.9 ± 2.1 |
|  | 18 months | F | +/+ | 726 ± 203 | 56 ± 24 | 24 ± 11 | 26.6 ± 3.4 |
|  |  |  | +/- | 747 ± 151 | 67 ± 16 | 25 ± 12 | 28 ± 3.1 |
LDLr -/- | 6 months | F | +/+ | 1599 ± 291 | 287 ± 130 | 58 ± 12 | 28.3 ± 4.8 * |
|  |  |  | +/- | 1600 ± 442 | 289 ± 119 | 51 ± 21 | 24.7 ± 3.4 * |
|  |  | M | +/+ | 1700 ± 427 | 477 ± 184 | 75 ± 25 | 35.8 ± 4.5 |
|  |  |  | +/- | 1723 ± 446 | 526 ± 223 | 76 ± 27 | 35 ± 4.2 |
|  | 10 months | F | +/+ | 1390 ± 387 | 267 ± 98 | 24.4 ± 7.1 | 28.6 ± 4.2 |
|  |  |  | +/- | 1343 ± 479 | 225 ± 71 | 20.8 ± 5.7 | 28.4 ± 3.4 |