Table 3 Clinical and metabolic characteristics of the hFH-P men and women (subgroup hFH-P).
| Â | hFH-P men n = 24 | hFH-P women n = 21 | p |
|---|---|---|---|
Age (years) | 34.0(9.8) | 55.0(11.5) | < 0.01 |
BMI (kg/m2) | 25.4(4.5) | 25.9(4.4) | 0.34 |
Waist (cm) | 98.0(13.5) | 85.0(15.0) | 0.01 |
TC (mg/dl) | 295.0(73.5) | 317.0(39.0) | 0.07 |
TG0 (mg/dl) | 138.5(89.5) | 156.0(78.0) | 0.66 |
TG2 (mg/dl) | 244.5(116.0) | 240.0(116.0) | 0.54 |
TG4 (mg/dl) | 308.5(130.8) | 266.0(122.0) | 0.12 |
TG6 (mg/dl) | 288.0(95.0) | 247.0(208.5) | 0.38 |
TG8 (mg/dl) | 202.0(87.0) | 206.0(190.0) | 0.86 |
TG AUC (mg/dl/h) | 2010.2(635.3) | 1665.7(958.6) | 0.14 |
TG i-AUC (mg/dl/h) | 934.2(427.1) | 707.5(358.1) | 0.04 |
HDL (mg/dl) | 37.0(6.8) | 55.0(20.0) | < 0.01 |
LDL (mg/dl) | 211.5(61.8) | 232.0(31.0) | 0.23 |
Apo AI (mg/dl) | 127.5(23.1) | 162.5(27.1) | < 0.01 |
Apo B (mg/dl) | 159.0(31.3) | 165.0(47.9) | 0.52 |
Lp (a) (mg/dl) | 15.5(15.6) | 15.9(30.5) | 0.30 |
Glu (mg/dl) | 90.0(10.0) | 96.0(21.0) | 0.26 |
TaqIB allele frequency, n (%) | Â | Â | Â |
B1 | 26 (54.2) | 25 (59.5) | 0.61 |
B2 | 22 (45.8) | 17 (40.5) | Â |
I405V allele frequency, n (%) | Â | Â | Â |
I | 33 (68.8) | 28 (66.7) | 0.83 |
V | 15 (31.2) | 14 (33.3) | Â |
S447X allele frequency, n (%) | Â | Â | Â |
S | 44 (91.7) | 38 (90.5) | 0.84 |
X | 4 (8.3) | 4 (9.5) | Â |