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Figure 6 | Lipids in Health and Disease

Figure 6

From: Oleic acid and peanut oil high in oleic acid reverse the inhibitory effect of insulin production of the inflammatory cytokine TNF-α both in vitro and in vivo systems

Figure 6

Robust decrease of blood glucose level in type type 2, but not in type 1 diabetic mice following 21 day peanut oil administration. Kunming mice were injected intraperitoneally with 40 mg/kg streptozocin to induce type1 diabetes. KKAy mice were maintained on a high fat diet for 10 days to induce type 2 diabetes. Once the mice were characterized to be diabetic, either type I or type II, 0.70 mL of peanut oil was administered by gavages to those mice for 21 days. Control mice were maintained on a standard diet and all other mice were maintained on a high fat diet. At the end of the experiments the fasting blood glucose levels were measured and expressed as mean ± SD (mM glucose) (p = 0.0004 between DM 2 and DM 2 + P. Oil; p = 0.0003 between control and DM 2 and p = 0.05 between control and DM 1).

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Lipids in Health and Disease

ISSN: 1476-511X