Figure 5
From: Haptoglobin inhibits phospholipid transfer protein activity in hyperlipidemic human plasma
a. Effect of Apo-A1 addition to the rate of PLTP activity within the first 60 minutes of reaction in hyperlipidemic plasma. Two and four micrograms of Apo-A1 were added to the plasma samples and PLTP activity was measured within the first two and 60 minutes to calculate the rate of activity (nmoles product/min). One of two representative experiments. b. Effect of Apo-A1 and Haptoglobin addition to the rate of PLTP activity within the first 60 minutes of reaction in hyperlipidemic plasma. Two micrograms of Apo-A1 and/or the equivalent of 100% of basal haptoglobin were added to the plasma (Pl: plasma alone, Pl+Apo-A1: plasma plus Apo-A1, Pl+Hp: plasma plus haptoglobin and Pl+Apo-A1+Hp: plasma plus Apo-A1 plus Haptoglobin) and PLTP activity was measured within the first two and 60 minutes to calculate the rate of activity (nmoles product/min). One of three representative experiments.