TY - JOUR AU - Zeggini, E. AU - Weedon, M. N. AU - Lindgren, C. M. AU - Frayling, T. M. AU - Elliott, K. S. AU - Lango, H. AU - Timpson, N. J. AU - Perry, J. R. AU - Rayner, N. W. AU - Freathy, R. M. PY - 2007 DA - 2007// TI - Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes JO - Science (New York, NY) VL - 316 UR - https://doi.org/10.1126/science.1142364 DO - 10.1126/science.1142364 ID - Zeggini2007 ER - TY - JOUR AU - Schulze, M. B. AU - Manson, J. E. AU - Ludwig, D. S. AU - Colditz, G. A. AU - Stampfer, M. J. AU - Willett, W. C. AU - Hu, F. B. PY - 2004 DA - 2004// TI - Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women JO - Jama VL - 292 UR - https://doi.org/10.1001/jama.292.8.927 DO - 10.1001/jama.292.8.927 ID - Schulze2004 ER - TY - JOUR AU - Dimitriadis, G. AU - Boutati, E. AU - Lambadiari, V. AU - Mitrou, P. AU - Maratou, E. AU - Brunel, P. AU - Raptis, S. A. PY - 2004 DA - 2004// TI - Restoration of early insulin secretion after a meal in type 2 diabetes: effects on lipid and glucose metabolism JO - European journal of clinical investigation VL - 34 UR - https://doi.org/10.1111/j.1365-2362.2004.01377.x DO - 10.1111/j.1365-2362.2004.01377.x ID - Dimitriadis2004 ER - TY - JOUR AU - El-Assaad, W. AU - Buteau, J. AU - Peyot, M. L. AU - Nolan, C. AU - Roduit, R. AU - Hardy, S. AU - Joly, E. AU - Dbaibo, G. AU - Rosenberg, L. AU - Prentki, M. PY - 2003 DA - 2003// TI - Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death JO - Endocrinology VL - 144 UR - https://doi.org/10.1210/en.2003-0410 DO - 10.1210/en.2003-0410 ID - El-Assaad2003 ER - TY - JOUR AU - Diakogiannaki, E. AU - Dhayal, S. AU - Childs, C. E. AU - Calder, P. C. AU - Welters, H. J. AU - Morgan, N. G. PY - 2007 DA - 2007// TI - Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells JO - The Journal of endocrinology VL - 194 UR - https://doi.org/10.1677/JOE-07-0082 DO - 10.1677/JOE-07-0082 ID - Diakogiannaki2007 ER - TY - JOUR AU - Nyblom, H. K. AU - Nord, L. I. AU - Andersson, R. AU - Kenne, L. AU - Bergsten, P. PY - 2008 DA - 2008// TI - Glucose-induced de novo synthesis of fatty acyls causes proportional increases in INS-1E cellular lipids JO - NMR in biomedicine VL - 21 UR - https://doi.org/10.1002/nbm.1197 DO - 10.1002/nbm.1197 ID - Nyblom2008 ER - TY - JOUR AU - Sargsyan, E. AU - Ortsater, H. AU - Thorn, K. AU - Bergsten, P. PY - 2008 DA - 2008// TI - Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells JO - The Journal of endocrinology VL - 199 UR - https://doi.org/10.1677/JOE-08-0251 DO - 10.1677/JOE-08-0251 ID - Sargsyan2008 ER - TY - JOUR AU - Zhang, R. AU - Barker, L. AU - Pinchev, D. AU - Marshall, J. AU - Rasamoelisolo, M. AU - Smith, C. AU - Kupchak, P. AU - Kireeva, I. AU - Ingratta, L. AU - Jackowski, G. PY - 2004 DA - 2004// TI - Mining biomarkers in human sera using proteomic tools JO - Proteomics VL - 4 UR - https://doi.org/10.1002/pmic.200300495 DO - 10.1002/pmic.200300495 ID - Zhang2004 ER - TY - JOUR AU - Sundsten, T. AU - Ostenson, C. G. AU - Bergsten, P. PY - 2008 DA - 2008// TI - Serum protein patterns in newly diagnosed type 2 diabetes mellitus – influence of diabetic environment and family history of diabetes JO - Diabetes/metabolism research and reviews VL - 24 UR - https://doi.org/10.1002/dmrr.789 DO - 10.1002/dmrr.789 ID - Sundsten2008 ER - TY - JOUR AU - Sundsten, T. AU - Zethelius, B. AU - Berne, C. AU - Bergsten, P. PY - 2008 DA - 2008// TI - Plasma proteome changes in subjects with Type 2 diabetes mellitus with a low or high early insulin response JO - Clin Sci (Lond) VL - 114 UR - https://doi.org/10.1042/CS20070323 DO - 10.1042/CS20070323 ID - Sundsten2008 ER - TY - JOUR AU - Sandler, S. AU - Bendtzen, K. AU - Eizirik, D. L. AU - Welsh, M. PY - 1990 DA - 1990// TI - Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro JO - Endocrinology VL - 126 UR - https://doi.org/10.1210/endo-126-2-1288 DO - 10.1210/endo-126-2-1288 ID - Sandler1990 ER - TY - JOUR AU - Holst, J. J. AU - Orskov, C. PY - 2004 DA - 2004// TI - The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism JO - Diabetes VL - 53 UR - https://doi.org/10.2337/diabetes.53.suppl_3.S197 DO - 10.2337/diabetes.53.suppl_3.S197 ID - Holst2004 ER - TY - JOUR AU - Briones, E. R. AU - Mao, S. J. AU - Palumbo, P. J. AU - O'Fallon, W. M. AU - Chenoweth, W. AU - Kottke, B. A. PY - 1984 DA - 1984// TI - Analysis of plasma lipids and apolipoproteins in insulin-dependent and noninsulin-dependent diabetics JO - Metabolism: clinical and experimental VL - 33 UR - https://doi.org/10.1016/0026-0495(84)90160-4 DO - 10.1016/0026-0495(84)90160-4 ID - Briones1984 ER - TY - JOUR AU - Hiukka, A. AU - Fruchart-Najib, J. AU - Leinonen, E. AU - Hilden, H. AU - Fruchart, J. C. AU - Taskinen, M. R. PY - 2005 DA - 2005// TI - Alterations of lipids and apolipoprotein CIII in very low density lipoprotein subspecies in type 2 diabetes JO - Diabetologia VL - 48 UR - https://doi.org/10.1007/s00125-005-1753-z DO - 10.1007/s00125-005-1753-z ID - Hiukka2005 ER - TY - JOUR AU - Juntti-Berggren, L. AU - Refai, E. AU - Appelskog, I. AU - Andersson, M. AU - Imreh, G. AU - Dekki, N. AU - Uhles, S. AU - Yu, L. AU - Griffiths, W. J. AU - Zaitsev, S. PY - 2004 DA - 2004// TI - Apolipoprotein CIII promotes Ca2+-dependent beta cell death in type 1 diabetes JO - Proceedings of the National Academy of Sciences of the United States of America VL - 101 UR - https://doi.org/10.1073/pnas.0403551101 DO - 10.1073/pnas.0403551101 ID - Juntti-Berggren2004 ER - TY - JOUR AU - Larsen, L. AU - Storling, J. AU - Darville, M. AU - Eizirik, D. L. AU - Bonny, C. AU - Billestrup, N. AU - Mandrup-Poulsen, T. PY - 2005 DA - 2005// TI - Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells JO - Diabetologia VL - 48 UR - https://doi.org/10.1007/s00125-005-0039-9 DO - 10.1007/s00125-005-0039-9 ID - Larsen2005 ER - TY - JOUR AU - Cai, Y. AU - Martens, G. A. AU - Hinke, S. A. AU - Heimberg, H. AU - Pipeleers, D. AU - Casteele, M. V. a. n. d. e. PY - 2007 DA - 2007// TI - Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation JO - Free radical biology & medicine VL - 42 UR - https://doi.org/10.1016/j.freeradbiomed.2006.09.018 DO - 10.1016/j.freeradbiomed.2006.09.018 ID - Cai2007 ER - TY - JOUR AU - Maedler, K. AU - Storling, J. AU - Sturis, J. AU - Zuellig, R. A. AU - Spinas, G. A. AU - Arkhammar, P. O. AU - Mandrup-Poulsen, T. AU - Donath, M. Y. PY - 2004 DA - 2004// TI - Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets JO - Diabetes VL - 53 UR - https://doi.org/10.2337/diabetes.53.7.1706 DO - 10.2337/diabetes.53.7.1706 ID - Maedler2004 ER - TY - JOUR AU - Oyadomari, S. AU - Mori, M. PY - 2004 DA - 2004// TI - Roles of CHOP/GADD153 in endoplasmic reticulum stress JO - Cell Death Differ VL - 11 UR - https://doi.org/10.1038/sj.cdd.4401373 DO - 10.1038/sj.cdd.4401373 ID - Oyadomari2004 ER - TY - JOUR AU - Merglen, A. AU - Theander, S. AU - Rubi, B. AU - Chaffard, G. AU - Wollheim, C. B. AU - Maechler, P. PY - 2004 DA - 2004// TI - Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells JO - Endocrinology VL - 145 UR - https://doi.org/10.1210/en.2003-1099 DO - 10.1210/en.2003-1099 ID - Merglen2004 ER - TY - JOUR AU - Fredenrich, A. PY - 1998 DA - 1998// TI - Role of apolipoprotein CIII in triglyceride-rich lipoprotein metabolism JO - Diabetes & metabolism VL - 24 ID - Fredenrich1998 ER - TY - JOUR AU - Krauss, R. M. AU - Herbert, P. N. AU - Levy, R. I. AU - Fredrickson, D. S. PY - 1973 DA - 1973// TI - Further observations on the activation and inhibition of lipoprotein lipase by apolipoproteins JO - Circulation research VL - 33 UR - https://doi.org/10.1161/01.RES.33.4.403 DO - 10.1161/01.RES.33.4.403 ID - Krauss1973 ER - TY - JOUR AU - Bury, J. AU - Rosseneu, M. PY - 1985 DA - 1985// TI - Enzyme linked immunosorbent assay for human apolipoprotein C-III JO - Journal of clinical chemistry and clinical biochemistry VL - 23 ID - Bury1985 ER - TY - JOUR AU - Malmendier, C. L. AU - Lontie, J. F. AU - Grutman, G. A. AU - Delcroix, C. PY - 1988 DA - 1988// TI - Metabolism of apolipoprotein C-III in normolipemic human subjects JO - Atherosclerosis VL - 69 UR - https://doi.org/10.1016/0021-9150(88)90288-2 DO - 10.1016/0021-9150(88)90288-2 ID - Malmendier1988 ER - TY - JOUR AU - Davidsson, P. AU - Hulthe, J. AU - Fagerberg, B. AU - Olsson, B. M. AU - Hallberg, C. AU - Dahllof, B. AU - Camejo, G. PY - 2005 DA - 2005// TI - A proteomic study of the apolipoproteins in LDL subclasses in patients with the metabolic syndrome and type 2 diabetes JO - Journal of lipid research VL - 46 UR - https://doi.org/10.1194/jlr.M500161-JLR200 DO - 10.1194/jlr.M500161-JLR200 ID - Davidsson2005 ER - TY - JOUR AU - Attia, N. AU - Durlach, V. AU - Roche, D. AU - Paul, J. L. AU - Soni, T. AU - Zahouani, A. AU - Landron, F. AU - Labrousse, F. AU - Leutenegger, M. AU - Girard-Globa, A. PY - 1997 DA - 1997// TI - Post-prandial metabolism of triglyceride-rich lipoproteins in non-insulin-dependent diabetic patients before and after bezafibrate treatment JO - European journal of clinical investigation VL - 27 UR - https://doi.org/10.1046/j.1365-2362.1997.790630.x DO - 10.1046/j.1365-2362.1997.790630.x ID - Attia1997 ER - TY - JOUR AU - Scheffer, P. G. AU - Teerlink, T. AU - Dekker, J. M. AU - Bos, G. AU - Nijpels, G. AU - Diamant, M. AU - Kostense, P. J. AU - Stehouwer, C. D. AU - Heine, R. J. PY - 2008 DA - 2008// TI - Increased plasma apolipoprotein C-III concentration independently predicts cardiovascular mortality: the Hoorn Study JO - Clinical chemistry VL - 54 UR - https://doi.org/10.1373/clinchem.2008.103234 DO - 10.1373/clinchem.2008.103234 ID - Scheffer2008 ER - TY - JOUR AU - Willer, C. J. AU - Sanna, S. AU - Jackson, A. U. AU - Scuteri, A. AU - Bonnycastle, L. L. AU - Clarke, R. AU - Heath, S. C. AU - Timpson, N. J. AU - Najjar, S. S. AU - Stringham, H. M. PY - 2008 DA - 2008// TI - Newly identified loci that influence lipid concentrations and risk of coronary artery disease JO - Nature genetics VL - 40 UR - https://doi.org/10.1038/ng.76 DO - 10.1038/ng.76 ID - Willer2008 ER - TY - JOUR AU - Ito, Y. AU - Azrolan, N. AU - O'Connell, A. AU - Walsh, A. AU - Breslow, J. L. PY - 1990 DA - 1990// TI - Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice JO - Science VL - 249 UR - https://doi.org/10.1126/science.2167514 DO - 10.1126/science.2167514 ID - Ito1990 ER - TY - JOUR AU - Maeda, N. AU - Li, H. AU - Lee, D. AU - Oliver, P. AU - Quarfordt, S. H. AU - Osada, J. PY - 1994 DA - 1994// TI - Targeted disruption of the apolipoprotein C-III gene in mice results in hypotriglyceridemia and protection from postprandial hypertriglyceridemia JO - The Journal of biological chemistry VL - 269 ID - Maeda1994 ER - TY - JOUR AU - Rutkowski, D. T. AU - Kaufman, R. J. PY - 2004 DA - 2004// TI - A trip to the ER: coping with stress JO - Trends Cell Biol VL - 14 UR - https://doi.org/10.1016/j.tcb.2003.11.001 DO - 10.1016/j.tcb.2003.11.001 ID - Rutkowski2004 ER - TY - JOUR AU - Khoo, S. AU - Cobb, M. H. PY - 1997 DA - 1997// TI - Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion JO - Proceedings of the National Academy of Sciences of the United States of America VL - 94 UR - https://doi.org/10.1073/pnas.94.11.5599 DO - 10.1073/pnas.94.11.5599 ID - Khoo1997 ER - TY - JOUR AU - Efanova, I. B. AU - Zaitsev, S. V. AU - Zhivotovsky, B. AU - Kohler, M. AU - Efendic, S. AU - Orrenius, S. AU - Berggren, P. O. PY - 1998 DA - 1998// TI - Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration JO - The Journal of biological chemistry VL - 273 UR - https://doi.org/10.1074/jbc.273.50.33501 DO - 10.1074/jbc.273.50.33501 ID - Efanova1998 ER - TY - JOUR AU - Unger, R. H. PY - 1995 DA - 1995// TI - Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications JO - Diabetes VL - 44 UR - https://doi.org/10.2337/diab.44.8.863 DO - 10.2337/diab.44.8.863 ID - Unger1995 ER -