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Figure 3 | Lipids in Health and Disease

Figure 3

From: Modulation Peroxisome Proliferators Activated Receptor alpha (PPAR α) and Acyl Coenzyme A: Cholesterol Acyltransferase1 (ACAT1) Gene expression by Fatty Acids in Foam cell

Figure 3

The effects of fatty acids (100 μM), Wy14643 (50 μmol/L) and Sandoz58-035 (5 μM) on mRNA levels of ACAT1 in THP-1 macrophages derived foam cells. Cells were treated for 48 h with fatty acids and pharmacological compounds. mRNA levels analyzed by cyber green procedures. The values normalized to β-actin. All results represent means ± SD from triplicate determinations, representative of 3 independent experiments compared with control. Significant differences between treatments are indicated by one-way ANOVA followed by Tukey multicomparison test. *P ≤ 0.05.

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Lipids in Health and Disease

ISSN: 1476-511X