A high oleic sunflower oil fatty acid esters of plant sterols mixed with dietary diacylglycerol reduces plasma insulin and body fat accumulation in Psammomys obesus

Table 2 PS-HOSO effect on body weight, liver weight and fat accumulation of phase C gerbils¹.

	Control			PS-HOSO
	Total	Non-fasting	Fasting	Total	Non-fasting	Fasting
Bodyweight at endpoint (gr)	219.05 ± 16.2	214.60 ± 15.8	222.75 ± 16.2	211.58 ± 19.8	216.63 ± 23.0	* 207.91 ± 17.3
Liver weight (gr)	8.23 ± 0.77	8.36 ± 0.80	8.12 ± 0.77	8.68 ± 1.19	* 9.40 ± 1.17	8.15 ± 0.93
Liver fat weight to liver weight ratio	0.11 ± 0.03	0.10 ± 0.02	0.11 ± 0.04	* 0.08 ± 0.01	0.08 ± 0.08	* 0.08 ± 0.01
Epididymal fat weight (gr)	6.35 ± 0.94	6.25 ± 0.96	6.43 ± 0.95	5.88 ± 1.73	6.54 ± 2.30	* 5.41 ± 1.06
Epididymal fat to liver weight ratio	0.78 ± 0.14	0.75 ± 0.12	0.80 ± 0.15	0.68 ± 0.18	0.69 ± 0.25	* 0.67 ± 0.14

Psammomys obesus were fed with Control or PS-HOSO as described in the method section and were monitored for body weight. Following 4.5 weeks of experimental diet feeding, half of each animal group was deprived of food for 16 h and then all animals were weighted and exsanguinated. The liver and epididymal fat were harvested and weighted. Liver fat of 15 PS-HOSO treated animals (9 and 6 from the fasting and non-fasting groups, respectively) and 16 control treated animals (7 and 9 from the fasting and non-fasting groups, respectively) was extracted and weighted.
Statistical significance between endpoint values of control and PS-HOSO treatments were calculated for all of phase C gerbils (total), and for fasting and non-fasting phase C gerbils.
¹Values are means ± S.D
*P < 0.05.
PS-HOSO: plant sterol esterified with high oleic sunflower oil.

ISSN: 1476-511X