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Figure 3 | Lipids in Health and Disease

Figure 3

From: Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver

Figure 3

Diagram showing increased indirect reverse cholesterol transport steps as a response to ciprofibrate treatment. Changes in the steps 3, 4 and 5 were verified in the present work, and other steps were previously described for different fibrates and animal species, as follow: Step 1: Chinetti G, et al. Nat Med. 2001;7:53-58; Step 2: Staels et al., 1992 and Bouly et al [ref [23, 47]]; Step 4: Berger & Moller, Annu Rev Med 2002;53:409-35; Step 5: Staels et al., 1992 [ref [47]]; Step 6: Mardones et al., 2003 [ref [51]]; Step 7: Staels et al., 1998 [ref [19]]. ABCA1: ATP-binding cassette transporter-A1; LCAT: lecithin cholesterol acyl transferase; LDLr: LDL receptor; LRP: LDL receptor related protein; SRB1:Scavenger receptor class B type I.

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