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Table 3 Effect of ciprofibrate treatment on the lipoprotein lipase (LPL) and hepatic lipase (LH) plasma activities.

From: Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver

Mice groups

LPL

(nmol FFA/mL/h)

LH

(nmol FFA/mL/h)

CIII

control

6231 ± 279 (5)

2732 ± 2981 (5)

 

treated

11990 ± 610 (5)c

3829 ± 1595 (5)

CIII/CETP

control

7188 ± 1244 (5)

3018 ± 550 (5)

 

treated

7620 ± 1993 (6)

3835 ± 611 (5)

CETP

control

3906 ± 2099 (7)

2863 ± 951 (5)

 

treated

8378 ± 1146 (6)b

2079 ± 328 (6)a

non-Tg

control

6724 ± 1126 (5)

3249 ± 806 (7)

 

treated

8957 ± 2984 (5)a

2706 ± 994 (5)a

  1. Normolipidemic (non-transgenic and CETP transgenic) and hypertriglyceridemic (CIII and CIII/CETP transgenic) mice were treated with ciprofibrate or vehicle (control) during 3 weeks. Mean ± SD (n). a p < 0.05; b p < 0.01; c p < 0.001 vs. control.