|
Gene symbol
|
Gene ID
|
Expression value ± SE
|
p value
|
|---|
|
Cyp7A1
|
1581
|
4.12 ± 2.68
|
0.012*
|
|
Cyp27A1
|
1593
|
1.10 ± 0.45
|
0.717
|
|
Nr0B2
|
604630
|
1.08 ± 0.52
|
0.788
|
|
Nr1H4
|
603826
|
0.83 ± 0.28
|
0.523
|
- Expression values represent the mean ± SE of GS subjects. Expression values for GS-free subjects were assigned as 1.00. Participants of the study were: GS, n = 12 (9 F/3 M), GS-free subjects, n = 10 (5 F/5 M). Age ranges were 50 ± 4 for GS and 56 ± 5 for GS-free. Gene ID corresponds to gene annotation obtained from NCBI. Cyp7A1, cytochrome P450, family 7, subfamily A, polypeptide 1 (cholesterol 7α-hydroxylase); Cyp27A1, cytochrome P450, family 27, subfamily A, polypeptide 1 (sterol 27α-hydroxylase); Nr0B2 nuclear receptor subfamily 0, group B, member 2 (short heterodimer partner); Nr1H4, Nuclear receptor subfamily 0, group H, member 4 (farnesoid x receptor, FXR).
