Gene symbol | Gene ID | Expression value ± SE | p value |
---|
Cyp7A1
| 1581 | 4.12 ± 2.68 | 0.012* |
Cyp27A1
| 1593 | 1.10 ± 0.45 | 0.717 |
Nr0B2
| 604630 | 1.08 ± 0.52 | 0.788 |
Nr1H4
| 603826 | 0.83 ± 0.28 | 0.523 |
- Expression values represent the mean ± SE of GS subjects. Expression values for GS-free subjects were assigned as 1.00. Participants of the study were: GS, n = 12 (9 F/3 M), GS-free subjects, n = 10 (5 F/5 M). Age ranges were 50 ± 4 for GS and 56 ± 5 for GS-free. Gene ID corresponds to gene annotation obtained from NCBI. Cyp7A1, cytochrome P450, family 7, subfamily A, polypeptide 1 (cholesterol 7α-hydroxylase); Cyp27A1, cytochrome P450, family 27, subfamily A, polypeptide 1 (sterol 27α-hydroxylase); Nr0B2 nuclear receptor subfamily 0, group B, member 2 (short heterodimer partner); Nr1H4, Nuclear receptor subfamily 0, group H, member 4 (farnesoid x receptor, FXR).