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Figure 1 | Lipids in Health and Disease

Figure 1

From: Cytotoxicity of unsaturated fatty acids in fresh human tumor explants: concentration thresholds and implications for clinical efficacy

Figure 1

Cytotoxic activity of UFAs exposed to micro-organs from malignant and normal tissue explants. A: Viability values (0 = sensitive, 1 = resistant) are shown for a metastatic ovarian tumor exposed to GLA (black square) and ALA (Grey square); 26 controls (represented as 0 μM GLA) were all viable. B: Results for a primary ovarian tumor. Viability values of 0 at 2 mM (two each for GLA, ALA) are not shown. Four control values were 1.0 (3) and 0.75 (1). C: Results for a glioblastoma tumor; 6 control were all viable. D: Results for a normal stromal tissue specimen; all 4 controls were viable. A numeric pair (m, n) depicts m and n identical results, respectively, for GLA and ALA represented by the bar below. All four experiments used 10% fetal calf serum.

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