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Figure 2 | Lipids in Health and Disease

Figure 2

From: Cytotoxicity of unsaturated fatty acids in fresh human tumor explants: concentration thresholds and implications for clinical efficacy

Figure 2

Aggregate data for UFA exposure to micro-organs from malignant tumor explants in 5-10% fetal calf serum. Viability values are shown for 153 micro-organ cultures from malignant tumors exposed to GLA (Black square) or ALA (Grey square) in 5% or 10% fetal calf serum. Tumor types tested, as detailed under methods, were ovarian adenocarcinoma, breast carcinoma, pancreatic carcinoma, melanoma, and glioblastoma. Parenthesized values above bars here and in the following two figures represent multiple data points as in Fig. 1. For example, at a 50 μM GLA concentration, the viability readings were 1.0 (resistant) for 4 micro-organ cultures, 0.5 (intermediate) for 2, and 0.25 (intermediate-sensitive) for 1.

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Lipids in Health and Disease

ISSN: 1476-511X