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Table 2 Baseline and Changes from Baseline in Total Cholesterol, LDL-C, HDL-C, Triglycerides, TC:HDL Ratio, Apo A and Apo B after 6 Weeks of Treatment with either the Combination of Ezetimibe plus Fenofibrate or Atorvastatin Monotherapy

From: Comparison of the efficacy of administering a combination of ezetimibe plus fenofibrate versus atorvastatin monotherapy in the treatment of dyslipidemia

 

Ezetimibe plus Fenofibrate

Atorvastatin Monotherapy

  
 

Baseline

6 Weeks

% Change

p Value

Baseline

6 Weeks

% Change

p Value

% Difference

p Value

Total Chol (mmol/L)

5.9

4.4

-25.1

< 0.001

5.8

4.4

-24.6

< 0.001

-0.4

0.806

LDL-C (mmol/L)

3.8

2.4

-34.6

< 0.001

3.7

2.3

-36.7

< 0.001

2.1

0.46

HDL-C (mmol/L)

1.4

1.5

10.0

0.002

1.3

1.5

8.9

0.006

1.1

0.778

Triglycerides (mmol/L)

1.5

1.0

-25.4

< 0.001

1.6

1.4

-14.5

0.002

-11.0

0.079

TC:HDL Ratio

4.3

3.0

-29.0

< 0.001

4.4

3.1

-28.7

< 0.001

-0.2

0.904

Apo A

1.27

1.32

4.5

0.041

1.29

1.30

1.5

0.493

3.04

0.295

Apo B

1.21

0.82

-31.8

< 0.001

1.19

0.82

-29.8

< 0.001

-1.99

0.392