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Table 3 Proteins that are either upregulated or downregulated in the brain of fat-1 transgenic mouse (see Ref. [46]).

From: Transgenic fat-1 mouse as a model to study the pathophysiology of cardiovascular, neurological and psychiatric disorders

Down-regulated proteins Fold change
Caspase 4 -1.74
Connexin 32 -1.71
HSP70 -1.69
cytokeratin 19 -1.64
cytokeratin 8.12 -1.63
TRF1 -1.59
cdk6 -1.56
Desmin -1.54
cytokeratin 13 -1.48
cytokeratin 7 -1.46
Calmodulin -1.46
pan Cytokeratin -1.45
Nedd8 -1.43
aCatenin -1.43
NTF2 -1.38
Dystrophin -1.38
Up-regulated proteins Fold change
Phospolipase A2 group V 1.40
FAK Phospo (pY577) 1.45
Nicastrin 1.46
b-NOS 1.46
CRK-L 1.47
S-100 1.47
SGK 1.48
Caveolin1 1.49
Bcl-xl 1.50
ARTS 1.50
i-NOS 1.51
CAM Kinase IV 1.52
PTEN 1.52
PAR4 1.52
Neurofilament 200 1.54
Gamma Tubulin 1.56
MAP Kinase(Erk1) 1.56
Phospolipase c gamma 1 1.56
MAPK activated protein kinase-2 1.56
EGF receptor 1.58
MAP Kinase activated phospotyrosine 1.58
ERK5 1.58
Protein phosphatase 1 1.60
p35 1.60
PAK phospo (Ps212) 1.60
PKC alfa 1.62
PKD 1.62
Glutamate receptor NMDAR 2a 1.63
S-100 beta 1.63
Protein phosphatase 1 1.64
FAK Phospo (pS772) 1.65
DOPA Decarboxylase 1.66
PKC gamma 1.66
NFKB 1.67
JNK activated diphospo 1.69
Tau Phospho (pS199/202) 1.79
Synuclein monoclonal 1.79
Estrogen Receptor 1.81
GRB-2 1.95
MAP Kinase activated phospothreonine 1.98