Skip to main content

Table 6 Predictive accuracy of the LAP as compared with those of BMI, WHpR, and WHtR.

From: Predictive performances of lipid accumulation product vs. adiposity measures for cardiovascular diseases and all-cause mortality, 8.6-year follow-up: Tehran lipid and glucose study

Factor

 

HR* (95% CIs)

Wald Χ2(P value)†

AIC

BIC

Discrimination¥

Calibration¶

Male

       
 

LAP

1.06 (0.89-1.26)

-

3134

3204

0.785 (0.756-0.813)

21.6 (0.010)

 

BMI

1.12 (0.94-1.33)

0.51 (0.474)

3133

3203

0.785 (0.759-0.811)

18.4 (0.031)

 

WHpR

1.25 (1.06-1.47)

4.62 (0.032)

3128

3198

0.788 (0.762-0.814)

18.0 (0.035)

 

WHtR

1.20 (1.00-1.43)

2.69 (0.101)

3131

3201

0.787 (0.759-0.814)

15.1 (0.088)

Female

       
 

LAP

1.41 (1.02-1.96)

-

1876

1947

0.846 (0.818-0.875)

12.2 (0.201)

 

BMI

1.15 (0.97-1.37)

0.81 (0.367)

1878

1951

0.847 (0.825-0.868)

12.8 (0.170)

 

WHpR

1.35 (1.10-1.65)

0.13 (0.718)

1872

1945

0.848 (0.820-0.876)

11.9 (0.218)

 

WHtR

1.30 (1.08-1.57)

0.17 (0.680)

1873

1946

0.849 (0.825-0.873)

12.6 (0.180)

  1. * Hazard ratios for one SD increment in each anthropometric variable and one SD increment in log LAP level, obtained from multivariate Cox proportional hazard regression model adjusted for age, smoking, systolic blood pressure, family history of premature CVD, diabetes, smoking, antihypertensive drug usage, HDL and non-HDL cholesterol, FPG, and 2h-PCPG , plus the TLGS intervention measures
  2. † Wald tests Χ2 (P value) of the linear hypotheses concerning the Cox regression models coefficients (paired homogeneity test) were performed to test the null hypotheses that the hazard ratios (effect size) for LAP were equal to those for BMI, WHpR, or WHtR.
  3. ¥ Assessed with C statistic (95% CIs)
  4. ¶ Assessed with Hosmer-Lemeshow Χ2 (P value)
  5. Abbreviations: AIC: Akaike information criteria; BIC: Bayesian information criteria; BMI: body mass index; LAP: lipid accumulation product; WHpR: waist-to-hip ratio; WHtR: waist-to-height ratio;
  6. Standard deviations: Men → LAP (mmol.cm) (naturally logarithmically-transformed),1.15; BMI (kg.m-2), 3.9; WHpR (%)7.0;WHtR 6.5 (%)
  7. Standard deviations: Women→ LAP (mmol.cm) (naturally logarithmically-transformed), 0.81; BMI (kg.m-2), 4.7; WHpR (%)8.3;WHtR 8.1 (%)