Effect of HDL composition and particle size on the resistance of HDL to the oxidation

Table 3 Comparison of the parameters of HDL oxidation between HDL particles derived from the low-HDL-C and control subjects

		Low-HDL-C	Control	P value
Lag time (minute)
	Total HDL oxidation	66.47	69.19	0.326
		(56.35 - 96.54)	(56.16 - 78.50)
	HDL₃ oxidation	69.40	64.04	0.206
		(55.75 - 96.51)	(54.44 - 82.45)
	P value	0.427	0.176
Propagation rate (nmol/mgHDL or HDL₃/min)
	Total HDL oxidation	1.242	1.543	< 0.0001
		(1.097 - 1.362)	(1.431 - 1.795)
	HDL₃ oxidation	1.032	1.022	0.533
		(0.924 - 1.123)	(0.807 - 1.159)
	P value	< 0.0001	< 0.0001
Maximal dienes (nmol/mgHDL or HDL₃)
	Total HDL oxidation	86.67	107.47	0.002
		(76.38 - 103.31)	(97.62 - 114.87)
	HDL₃ oxidation	71.47	71.57	0.646
		(63.26 - 78.45)	(60.89 - 84.22)
	P value	< 0.0001	< 0.0001

Data are expressed as median (lower and upper quartile). Statistical significances were adjusted for age, sex, and smoking status between low HDL and control subjects.

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