Levels of p-eIF2α, CHOP and cleaved caspase-3 in MIN6 cells with reduced SCD1 levels. MIN6 cells were transfected with siRNA targeted towards SCD1 (black bar) or with nonsense siRNA (mock; white bar). After 72 hours culture, protein levels of p-eIF2α, CHOP and cleaved caspase-3 were measured. Results are means ± SEM from 4-6 individual experiments. *P < 0.05 denotes difference compared to mock-transfected cells.